Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
CG11294 (FBgn0030058) TF
 
(-0.14/-1.60/1.34)

Factor activity

H. sapiens orthologues1

OTX2 (HGNC:8522, ENSG00000165588), OTX1 (HGNC:8521, ENSG00000115507), CRX (HGNC:2383, ENSG00000105392)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGGCAGGTCCTTTTATATCACCGCTGCCCGGCGATCTGCTCACGGAGTATATGTTTGGCCGTAGGCGACAGCGCCGGAACCGGACGACCTTCACGCCACAGCAGCTGCAGGAGCTGGAGGCACTCTTCCAGAAGACCCACTATCCCGACGTCTTCCTGCGCGAGGAGGTGGCCCTGAGGATCAGCCTCAGCGAGGCACGCGTCCAGGTGTGGTTCCAGAATCGCCGGGCCAAGTGGCGCAAGCAGGCACGACTGCAGCTCCTCCAGGACGCCTGGCGGATGCGCTGCCTCAGCCTGGGCACGCCCCCCGTCATGGGCGGTGGAGCGGTGCAGGGCGGATCCGGCAACGGAGCTACGGCTCGACCGCCCAGCCAGACGCCGGAGAACCTCTCTTCCGCGAGCAAGGATTCGGAACTGGCGGAGGTGGGCAATGGACCCAATTCGGGGAGCTTCACCATGATGCACCCGGCATTCCAGCAGCAGCATCAGCAACAACAGCACCAGGGACACCAGCAGGCCACGGATCAGGATAAGCTATCGAAGACCTATACAGAACTAAAGCTCTATAAGGCGCCGTCGCACGGCATGGAACTGGGCGGAATGGCCGCCCTATCCGGACACTCCGACGAGGGTTCCGATGGATCCGATTCCGAGGAGATTGATCTCACCTCCGGCGCCTGTATCGATTTCTCCCAGAGCAGCAAGCTCCAGCAGCAGCAGCAGCAGCAACAACAACAGGGAACTCAGGGGGCGGCGGGATCAGCGGAGGCGAATGGAGGCCTG

CDS AA Sequence2

MAGPFISPLPGDLLTEYMFGRRRQRRNRTTFTPQQLQELEALFQKTHYPDVFLREEVALRISLSEARVQVWFQNRRAKWRKQARLQLLQDAWRMRCLSLGTPPVMGGGAVQGGSGNGATARPPSQTPENLSSASKDSELAEVGNGPNSGSFTMMHPAFQQQHQQQQHQGHQQATDQDKLSKTYTELKLYKAPSHGMELGGMAALSGHSDEGSDGSDSEEIDLTSGACIDFSQSSKLQQQQQQQQQQGTQGAAGSAEANGGL

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.