Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
Sox100B (FBgn0024288) TF
 
(-0.49/-2.50/0.73)

Factor activity

H. sapiens orthologues1

SOX8 (HGNC:11203, ENSG00000005513), SOX9 (HGNC:11204, ENSG00000125398), SOX10 (HGNC:11190, ENSG00000100146)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGAGTGACAGTTCCAGCTCCAATTGCTCGAAGGATCGTGCTAAGCCGGTGGAAACGCTGGTTTTGGCAAACTATGCCCTGAAAGCCGAGCAGAAGAAGGCCCAAGGACAGGGTGGTCGAAAGGAGGACGAGCGCATCACCACTGCGGTTATGAAGGTCCTCGAGGGCTACGACTGGAATCTAGTCCAGGCATCAGCCAAGGCGCCCACGGACCGCAAAAAGGAGCACATCAAGCGACCGATGAACGCCTTCATGGTTTGGGCCCAGGCAGCCCGCAGGGTCATGTCCAAACAGTATCCGCATCTGCAGAACTCCGAACTGAGCAAATCGCTGGGCAAGCTGTGGAAAAATCTAAAGGACAGTGATAAGAAGCCCTTCATGGAATTCGCCGAGAAGCTTCGAATGACCCACAAGCAGGAGCATCCGGACTACAAGTACCAGCCGCGGCGCAAGAAAGCGCGGGTGTTGCCGTCCCAGCAAAGCGGTGAAGGGGGATCCCCGGGTCCAGAGATGACGTTATCCGCCACTATGGGTAGCTCCGGGAAGCCAAGGAGCAGCAATTCCAATGGCCAGAGGCGAGCGGGCAAGGGAAATGCAGCTGCTGATCTGGGCAGCTGCGCCTCGACCATCTCCCATGCCAATGTGGGCTCGAACTCCTCGGATGTCTTCAGTAATGAGGCCTTCATGAAATCCCTGAACAGTGCCTGTGCGGCCAGTTTGATGGAGCAGAGCCTCATCGAAACTGGCCTGGACTCTCCGTGCTCCACGGCCAGTTCAATGTCCTCGCTGACGCCCCCAGCCACGCCCTACAATGTAGCCCCATCCAATGCAAAAGCGTCGGCAGCAAATAACCCCAGTCTTTTGCTAAGGCAACTAAGTGAGCCAGTTGCAAATGCAGGCGATGGTTATGGAGTTCTCCTCGAGGCAGGCAGAGAATATGTGGCCATAGGTGAGGTCAATTATCAGGGGCAATCGGCGGGAGTTCAGAGTGGAGCCGAAGGAGGAGGAGCAGGTCAGGAGATGGACTTCCTGGAGAACATCAATGGGTATGGTGGCTACACGGGCAGTCGGGTGAGCTACCCTGCCTACTCCTACCCCGCAAACGGAGGCCACTTCGCCACCGAGGAGCAGCAGCAGCAGCAGGCGTTACAGGCCAGTGAAGCCTTAAATTACAAGCCAGCAGCCGCCGACATCGATCCCAAGGAAATTGACCAGTATTTCATGGATCAAATGCTGCCCATGACGCAGCACCACCATCCGCATCACACCCACCCGCTGCACCACCCACTGCACCACTCGCCGCCTTTGAACTCCTCCGCCTCGCTATCCTCGGCCTGCTCCAGTGCCAGCTCGCAGCAGCCGGTAGCGGAGTACTACGAGCACTTGGGCTACTCCCCGGCCGCCTCCTCTGCCAGCCAGAATCCCAACTTCGGGCCCCAGCAACCGTATGCCAACGGGGCGGCCTCCATGACACCCACACTGGGTGACCCCGCACCGCAACAGGAGCTGCAGTCGCAGCAGCAGGAGCAGCAGCACCAGAATCCATCGCAGCATCATCTGTGGGGCACTTACACTTATGTCAATCCC

CDS AA Sequence2

MSDSSSSNCSKDRAKPVETLVLANYALKAEQKKAQGQGGRKEDERITTAVMKVLEGYDWNLVQASAKAPTDRKKEHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFMEFAEKLRMTHKQEHPDYKYQPRRKKARVLPSQQSGEGGSPGPEMTLSATMGSSGKPRSSNSNGQRRAGKGNAAADLGSCASTISHANVGSNSSDVFSNEAFMKSLNSACAASLMEQSLIETGLDSPCSTASSMSSLTPPATPYNVAPSNAKASAANNPSLLLRQLSEPVANAGDGYGVLLEAGREYVAIGEVNYQGQSAGVQSGAEGGGAGQEMDFLENINGYGGYTGSRVSYPAYSYPANGGHFATEEQQQQQALQASEALNYKPAAADIDPKEIDQYFMDQMLPMTQHHHPHHTHPLHHPLHHSPPLNSSASLSSACSSASSQQPVAEYYEHLGYSPAASSASQNPNFGPQQPYANGAASMTPTLGDPAPQQELQSQQQEQQHQNPSQHHLWGTYTYVNP

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.