Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
MBD-like (FBgn0027950) cofactor
 
(-1.31/-4.33/-0.34)

Factor activity

H. sapiens orthologues1

MBD2 (HGNC:6917, ENSG00000134046), MBD3 (HGNC:6918, ENSG00000071655)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGCAAATGAACCCGAGCGTCACAATCGAGCGCAAACGCGTCGACTGCAGTGTCCTGCCAAAGGGATGGCAGCGCGACGAGGTCCGAAAGTCCGGCAGCAGCGCCAATAACAACGCCAGCAGCAACAACAACAGCAGTGCCACAGCCAGCAGCAACAACAACAATAACAAGGTGGATGTTTTCTACTACAGTCCCACAGGAAAAAGGGCGGAGGGAAAGCCACAGGACATTGCAATCCCTGATTTCCAGCCTGGCAAAATGCCGCACTGCGCCCTGCCCTCGCCCTCCATTTCGCTGTACCGCTGCAGCGCCATGCCGCTGCCTATAGCAAGCGGGGGCGGTAATGGGGCCACCAGCGGATCGGCGGCCAATGCCCTCAAGCGCAAGTTCGCCCGGAGTCAAGGAGGCAATGCTGCAGGAGCAGCAGGAGCTGCTCCTCCGGCAGCGACCGCCTCGTCAGCAGCAACAGCGACAGCAGCATCTGCTTCACCATCAACGGCCAATCGCCAGCAGCAACAGATCGAACTCAGCCGAGCCCTGCGCACTGATGTCTCCCTGGTGCCTCCCATTCGACAGACTGCCTCGATCTTCAAGCAACCGGTGACGGTGATTCGCAACCATAAACAGGATCCCGCCAAAGCGAAGAATGAACCCAAGCATGGCACTCGGGAGAAGCCGAAACAGCTGTTCTGGGAGAAGCGACTGGAACGACTACGCGCCTGCCACGACAGTGGCGAGGAGCTAGACGACATCTCACTGCCCAAGACCATACGCACCGTTGGCCCCAATGTCAACGAACAGACCGTCCTCCAGTCGGTGGCCACGGCCCTGCATATGCTCAACGCCGGCGTACACGGCCAGAGTTCTACGAAGGCTGATTTGACCAAGAATGCCATGGCGTTTATGAATCCTGAACAACCGCTAATGCACGCGGTGATCATTTCGGAGGACGACATACGCAAACAGGAGGATCGGGTCGGAGTTGCGCGGCGAAAGCTGCAGGATGCACTCAAGACA

CDS AA Sequence2

MQMNPSVTIERKRVDCSVLPKGWQRDEVRKSGSSANNNASSNNNSSATASSNNNNNKVDVFYYSPTGKRAEGKPQDIAIPDFQPGKMPHCALPSPSISLYRCSAMPLPIASGGGNGATSGSAANALKRKFARSQGGNAAGAAGAAPPAATASSAATATAASASPSTANRQQQQIELSRALRTDVSLVPPIRQTASIFKQPVTVIRNHKQDPAKAKNEPKHGTREKPKQLFWEKRLERLRACHDSGEELDDISLPKTIRTVGPNVNEQTVLQSVATALHMLNAGVHGQSSTKADLTKNAMAFMNPEQPLMHAVIISEDDIRKQEDRVGVARRKLQDALKT

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.