Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
Orc1 (FBgn0022772) cofactor
 
(-0.58/-3.44/0.30)

Factor activity

Additional information

Orc1 [FlyBase] | Orc1 [FlyMine] | Orc1 [BDGP]

H. sapiens orthologues1

ORC1 (HGNC:8487, ENSG00000085840)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGGTTAATAAAGAGAACGCCCGCAGTGTGGGCCAGCAGGTGAAGTGGATCGGAAGCCAAGACGAACTGCCGCCGGTGAAGAATCTGGAGCACAAGAACGTCTACTTCTACCAGAAGTGCATCTACGGTCCGCTGACTTTGTCCGTTGGCGACTTTATACTGGTGTCGAACGCGGATGCCGCCGAGCCGGACACAGTGAGTGGATGCGACGTGGCCCGGATCCTGCACATGTACGAGCTGCGCGAGCTGACCGATCGCGAGCCCTGCCGCGCCATCGTCCAGTGGTACTCCTGGCCGAAAGCCATTCCGCACAACAAATACGACGACGACGAGGTGGCCATAGACTTTAGCCTGGAGGTGATCGAGGAGCATCGCCCGTACGACAACGACGTGGCCCTCGGTGCCATCTATCGCAAGTGCATCGTGCTGGAGGGTACCTCAAAAACGTCAGCGGAGGAGATTCTCAAACGACACGCCAACAAACTGAAGTCCACGGCCTGCCCCATGTTTGTCAGCCGGTACAGGTTTGTCAAGGTGAAGCGGAGCTATCGCTTGATTCCCTTGGAAATTCACTTGGAGCAGCCGGAGGACAATGCCAGGCCAACCCGCTCATCTCGCAAATCCCTAACTGCACACAGAGAATCCAAGCGATCAATATCCGCCCGCCACGATGACACAGCTGGCAACAAGGGATCCTCAGTGGAAAAACGACGACGTGCGTCCATGGCAGCCTCGAGTTCCGTGGAGTTCATCGATGTCAACAGCTTCATCTGCGAGAATAAAGTGTCGCCAATTAAGATCGTGGGCGGACGCAGTGTCGTCCGGTTGTCTGAGAAGAAAAATGCTCCGGAGATCAATGCCAACTATCTGCCGGCTTCGCCTCTCACTGAGAAGAACGCCAAGGTGGAGACACCGAAATCCCGGGCCTCGGCAGCCCGCCGCAACCTAAATCTCAGCCTGGATCGCGGAGCCGACACCACAGCCGACTCAGACTGCCTGAACTACTCCATTGTTCAGCAGACTCCCGATCCTAAAACGCCTTCCAACGACATGAAGATCAAGCTGCGCCTTTCGGAGAGAAGGCGTTCGGTGCGCCTCGCATCCATGGACGTGGATCCCTTGTCGTTAGAGGAGGCCGTACAAGAACCCAATGCCCAGGGACGCAAGCGATTGGGCGTGGCCAATGGCGATATCTACCATACGCCCACCAAGAAATCCAAAGAGCCTCTGGAATCAGCTGCAGCTACCGAGCAAACGCCCTCGACGAGGCGTAAAAGCATCCTGAAATCAGCAACTAGTCGATTGGCCGAGGGCACGCCCAGGCGCAGTATTCACCTCTCGAACATTGTGGAGCAGCGCGTGTTTGAGGATGATGAAATAATATCCACTCCGAAAAGGGGGCGCTCGAAGAAAACAGTTCAAGACAATGACGAGGACTATTCGCCAAAGAAATCGGTCCAAAAGACGCCAACACGAACGCGTCGGTCAAGCACCACCACCAAAACAGCGACGACACCCAGCAAAGGGATCACAACCGCAACTGCAACCCCGATGACGCCCTCCCAAAAGATGAAGAAGATACGAGCCGGTGAACTTAGTCCCAGCATGCAACAGCGCACTGACCTTCCGGCCAAGGATTCCAGCAAATCCGAACTGCAGCTAGCACGCGAACAGCTTCATGTGTCTGTTGTGCCAAAGAGTTTGCCGTGCCGAGAACGGGAATTCGAGAACATTTACGCCTTTCTGGAGGGCAAGATCCAGGATCAGTGCGGCGGCTGCATGTATGTGTCCGGAGTTCCGGGCACTGGCAAAACAGCCACTGTCACTGGCGTCATACGCACCCTGCAGAGGATGGCTAAACAGAATGAGCTGCCTGCCTTTGAGTATCTGGAGATTAATGGCATGCGACTGACTGAGCCGCGTCAGGCCTACGTCCAGATCTACAAACAGCTCACGGGCAAGACTGTGTCCTGGGAGCAGGCACACGCTCTGCTAGAGAAACGGTTCACTACTCCGGCGCCGCGTAGAGTTACCACTGTGCTGCTGGTTGATGAGCTGGATATCTTGTGCAACCGGCGCCAAGATGTGGTCTACAATTTGCTCGACTGGCCCACCAAGTCGGCGGCCAAGCTGGTAGTGGTCACCATTGCCAACACCATGGACTTGCCTGAGCGCTTGCTGATGGGTAAAGTCACCTCTCGTCTTGGACTTACCCGTCTCACATTCCAGCCGTACAGCCACAAGCAGCTGCAAGAGATCGTTACCGCCCGCCTGGGAGGATCGGAGACTTTTAAAGGCGAGGCCGTGCAGCTGGTGGCGCGCAAGGTAGCCGCCGTTTCCGGTGATGCTCGCCGAGCTCTGGACATCTGCCGGCGTGCTACAGAAATTGCTGATACGGCTGCGGTCAAGTGCGTCACAATGCTGCACGTGCAGCAGGCATTGGCCGAGATGATAGCCAGTGCCAAGGTGCAGGCCATTAGGAACTGTTCGCGGATGGAGCAGATCTTCTTGCAGGCAATTGCAGCTGAAGTTACGCGCACTGGCGTCGAGGAGACGACTTTCATGGGCGTCTATCAGCAGGTGGAAACTATTGCCGCCTTCATGGGCGTGACCTTTCCACCACCAGGACGCGCCCTGCGCTTGTGCTCCAAGCTGGGCGCCGAGCGACTCATCATCAGTGAACATTCCCGCAATGACCTCTTTAAGAAAATCCTGCTCAACGTCAGCGCTGATGACATTCACTACGCCCTCAGAGTGGAAGAGATGGTCAAC

CDS AA Sequence2

MVNKENARSVGQQVKWIGSQDELPPVKNLEHKNVYFYQKCIYGPLTLSVGDFILVSNADAAEPDTVSGCDVARILHMYELRELTDREPCRAIVQWYSWPKAIPHNKYDDDEVAIDFSLEVIEEHRPYDNDVALGAIYRKCIVLEGTSKTSAEEILKRHANKLKSTACPMFVSRYRFVKVKRSYRLIPLEIHLEQPEDNARPTRSSRKSLTAHRESKRSISARHDDTAGNKGSSVEKRRRASMAASSSVEFIDVNSFICENKVSPIKIVGGRSVVRLSEKKNAPEINANYLPASPLTEKNAKVETPKSRASAARRNLNLSLDRGADTTADSDCLNYSIVQQTPDPKTPSNDMKIKLRLSERRRSVRLASMDVDPLSLEEAVQEPNAQGRKRLGVANGDIYHTPTKKSKEPLESAAATEQTPSTRRKSILKSATSRLAEGTPRRSIHLSNIVEQRVFEDDEIISTPKRGRSKKTVQDNDEDYSPKKSVQKTPTRTRRSSTTTKTATTPSKGITTATATPMTPSQKMKKIRAGELSPSMQQRTDLPAKDSSKSELQLAREQLHVSVVPKSLPCREREFENIYAFLEGKIQDQCGGCMYVSGVPGTGKTATVTGVIRTLQRMAKQNELPAFEYLEINGMRLTEPRQAYVQIYKQLTGKTVSWEQAHALLEKRFTTPAPRRVTTVLLVDELDILCNRRQDVVYNLLDWPTKSAAKLVVVTIANTMDLPERLLMGKVTSRLGLTRLTFQPYSHKQLQEIVTARLGGSETFKGEAVQLVARKVAAVSGDARRALDICRRATEIADTAAVKCVTMLHVQQALAEMIASAKVQAIRNCSRMEQIFLQAIAAEVTRTGVEETTFMGVYQQVETIAAFMGVTFPPPGRALRLCSKLGAERLIISEHSRNDLFKKILLNVSADDIHYALRVEEMVN

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.