Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
fd96Cb (FBgn0004898)	TF	(-0.83/-3.31/0.30)	11	◼	◻	◻	◻	◻

Factor activity

Celltype:
S2

Additional information

fd96Cb [FlyBase] | fd96Cb [FlyMine] | fd96Cb [BDGP]

H. sapiens orthologues¹

FOXB1 (HGNC:3799, ENSG00000171956), FOXB2 (HGNC:23315, ENSG00000204612)

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
ind	0.585 (1)
HLHm3	0.593 (2)
h	0.703 (3)
fd64A	0.730 (4)
CG6808	0.799 (5)

All TFs

Cofactor	Euclidean distance (rank)
CG14220	1.447 (1)
XNP	2.167 (2)
HP1b	2.193 (3)
Bin1	2.310 (4)
Mi-2	2.420 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
h	0.988 (1)
HLHm3	0.988 (2)
ind	0.987 (3)
kni	0.986 (4)
CG6808	0.983 (5)

All TFs.

Cofactor	Pearson correlation (rank)
Su(var)205	0.955 (1)
Su(z)2	0.951 (2)
CG14220	0.950 (3)
H	0.949 (4)
Psc	0.932 (5)

All cofactors.

CDS DNA Sequence²

ATGCCACGCCCATTGAAAATGAGCTACGGTGATCAGAAGCCTCCCTACTCGTACATATCATTAACGGCCATGGCCATAATACACTCGCCGCAAAGATTGCTGCCGCTCAGTGAGATATATCGATTTATAATGGATCAGTTTCCATTCTACCGGAAGAACACGCAAAAGTGGCAAAACTCACTGCGGCACAATCTCAGCTTCAACGATTGCTTCATCAAGGTGCCGAGGAATGTGACCAAGGCCGGCAAGGGCTCCTACTGGACACTTCATCCCATGGCCTTCGATATGTTCGAGAATGGCAGCCTGCTGCGGCGGCGAAAACGTTTCCGCGTCAAGCAGCTCGAGAAGGATATTTCGAACTGGAAATTAGCCGCCGCCGCCAATACGGAGATGGTGACCCACTATCTGGACGATCAGCTAACGCAGATGGCCTTTGCCGATCCGGCGCGGCATGGTCATGTGCTCGCCAATGCATCTGCTGCCCAAATGTCACCCTACAAGGCTACTCCGCCGATCCTTCCGACGACTGTGACCCAACTTCCGGCGCGGCCAAAGCGCGCCTTCACCATCGAGAGTCTCATGGCTCCGGATCCGGCGAGCACGCCAAATGAGGGATTAGTGCCCATGGAGTACGGCAGTCCCGATGCCGTCGCGTTGGAAAAGCCGCCGTTTAATTTGCCATTCAATTTCAACGAACTCGCCGCGCAGTATCAGTTATACTTCCCAAGTTTTTTCTACAACGGCCAATATGGCAACATACCTTGCTACCAGAAAACACCGCCGCTTTTTCATAACGGCCCGTTGCCCGTCTTT

CDS AA Sequence²

MPRPLKMSYGDQKPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVPRNVTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQLEKDISNWKLAAAANTEMVTHYLDDQLTQMAFADPARHGHVLANASAAQMSPYKATPPILPTTVTQLPARPKRAFTIESLMAPDPASTPNEGLVPMEYGSPDAVALEKPPFNLPFNFNELAAQYQLYFPSFFYNGQYGNIPCYQKTPPLFHNGPLPVF

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.