Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
CG12081 (FBgn0030053)	cofactor	(-0.15/-2.79/0.67)	6	◼	◻	◻	◻	◻

Factor activity

Celltype:
S2

Additional information

CG12081 [FlyBase] | CG12081 [FlyMine] | CG12081 [BDGP]

H. sapiens orthologues¹

KLHDC3 (HGNC:20704, ENSG00000124702)

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
Mtp	1.805 (1)
Met	1.815 (2)
Crg-1	1.911 (3)
CG1407	1.979 (4)
Pbp95	1.979 (5)

All TFs

Cofactor	Euclidean distance (rank)
SNF4Agamma	0.843 (1)
Hdac3	0.869 (2)
Hira	0.924 (3)
Mkrn1	1.024 (4)
alpha-Adaptin	1.111 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
Mtp	0.926 (1)
Met	0.906 (2)
CG33936	0.896 (3)
CG11906	0.887 (4)
Crg-1	0.885 (5)

All TFs.

Cofactor	Pearson correlation (rank)
CG9426	0.988 (1)
Nat1	0.988 (2)
CG8830	0.986 (3)
CG6805	0.983 (4)
Hdac3	0.982 (5)

All cofactors.

CDS DNA Sequence²

ATGCTGTGGACGGTGCATCTGGACGGTGGGCCACAGCGGGTCAATCACGCAGCGGTGGGCGTGGGCGACTTCATCTACAGCTTTGGTGGCTACTGCACCGGATACGATTATCGCTACAATGAGCCCATCGATGTGCACGCCCTGAATGCACACACAATGCGCTGGACTCTGGTGCCCCAGCAGCTGGACGACGCGGGTGTGCCACTCAAGTATCCGCTGGTGCCCTTCCAGCGCTACGGACACACGGTGGTGGCCTACAAGGATCGCATCTACATTTGGGGCGGTCGCAACGACGAGAATCTCTGCAATACCCTCTACTGCTTCGATCCCAAGACAGCGCAGTGGTCGAGGCCCCAGGTCACTGGCTGTCTACCCGGAGCGCGGGATGGTCACTCGGCCTGTGTCATTGGCAATAGTATGTACATCTTCGGTGGATTCGTCGATGAGATCAACGAGTTCAGCAGCGATGTGCATTCCCTTAATCTGGACACCATGGAGTGGCGCTATGTTCAGACATTTGGCGTGCCGCCCAGCTACAGAGATTTTCATGCGTCGGTGGCCTACGAACAGGAGCGAATGTACATCTTCGGCGGGCGGGGCGATAAGCACAGTCCGTACCACAGCCAGGAGGAGACCTACTGTCACGAGATCGTCTACCTGGACATGAAGACCAAGGTGTGGCATCGACCGTTCACGGCCGGTAAGGTGCCCGTTGGTCGACGCAGCCACAGCATGTTCGTTTACAACAAGCTGATATATGTCTTCGGTGGCTATAATGGCCTGTTGGATCAGCATTTCAACGATCTGTACACCTTCGATCCGCGCACCAAGCTGTGGAACCTGATACGGGCCAACGGCAAGGCACCGACGGCGCGTCGGAGACAGTGCGCCATTGTGATGGGCACTAGGATGTTCCTGTTTGGCGGCACCAGTCCAAGGAGCGGCTCCTCCAGCTCGCCGGCAGCTGTTTCACCCACTCAAGAGACGGGCGGAGCCGCAGCGGCTGGCGGAGTTGTTCCGCCCGGTGTGGCGCTTATCGACTACAGCGATCTGCATGTGCTCGACTTTGAGCCCACTCTAAAAACCCTGGCCACCATGGTGGTGCTCAAGCACCAGCTGGACATCTCGGGGCTGCCAAGGAGCTTCCGCTCGGACCTGCAGATGCTGACACAGCCGAACAGTATTAGCCGGCCCATCAACCAAGCTGGC

CDS AA Sequence²

MLWTVHLDGGPQRVNHAAVGVGDFIYSFGGYCTGYDYRYNEPIDVHALNAHTMRWTLVPQQLDDAGVPLKYPLVPFQRYGHTVVAYKDRIYIWGGRNDENLCNTLYCFDPKTAQWSRPQVTGCLPGARDGHSACVIGNSMYIFGGFVDEINEFSSDVHSLNLDTMEWRYVQTFGVPPSYRDFHASVAYEQERMYIFGGRGDKHSPYHSQEETYCHEIVYLDMKTKVWHRPFTAGKVPVGRRSHSMFVYNKLIYVFGGYNGLLDQHFNDLYTFDPRTKLWNLIRANGKAPTARRRQCAIVMGTRMFLFGGTSPRSGSSSSPAAVSPTQETGGAAAAGGVVPPGVALIDYSDLHVLDFEPTLKTLATMVVLKHQLDISGLPRSFRSDLQMLTQPNSISRPINQAG

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.