Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
trr (FBgn0023518)	cofactor	(-0.64/-2.50/1.34)	12	◼	◼	◼	◼	◼

Factor activity

Celltype:
S2
Kc167
BG3
OSC
HeLa

Additional information

trr [FlyBase] | trr [FlyMine] | trr [BDGP]

H. sapiens orthologues¹

None.

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
CG11906	2.083 (1)
Vsx2	2.086 (2)
Hr78	2.160 (3)
HLHm7	2.422 (4)
ATbp	2.430 (5)

All TFs

Cofactor	Euclidean distance (rank)
Mnn1	1.915 (1)
Bre1	2.021 (2)
Keap1	2.077 (3)
chm	2.109 (4)
CG13796	2.166 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
srp	0.910 (1)
Mtp	0.829 (2)
Crg-1	0.815 (3)
bun	0.808 (4)
CG11906	0.806 (5)

All TFs.

Cofactor	Pearson correlation (rank)
CG1826	0.886 (1)
chm	0.859 (2)
Parg	0.832 (3)
UbcD6	0.832 (4)
CG13690	0.831 (5)

All cofactors.

CDS DNA Sequence²

ATGAATATACCGAAGGTGACAACATCGCTTGGTGCCGCCGAAAAGGCGAAACCCGAAAGAGTAGCATCCGTGGCCGCCGCTGCCTTCAATGCGGTCAGCCTGCAGAAGCGCAGCGGCGACGACACCGCCACTCCGGCGGAGGATCCCACGCGCAAGAAGGCCAAGACGGAGCTGCTTTTCGGAACTGGAACGGCAGCGCCCAGTTTGCCCGCCAAAGCGTCGAGCACCGCGCCGCAGCAGCTCCTCTACCAGCGGAGTGGACAGCAGGCTAAGGCGCAGGTAAAAGCTGCGTCGGAGCCGCAGGATGTCGAGACGGCGGACGGCGTCTGGGACGCCCGCGATCAGCAGATCATAGTGTGCAACTTCGGCTCCGGCACTGAGATGGGTGCCATCAAGGCGGAGGACGCTGACAAGCAGACCTTTACCAGCTTTACCAAAAAGGAGGGTGCCTCATCGTCGGCCTCGTCATCATCGTCAACCGCGTCCGTCATTTCCATCGAGCCCAGTGGCTCGGGGCAGGATCATGCTGAAAACTCCGGCAAATCTGAGGACCTCGACTACGTACTGATGCCAGCCAGCGGCGCGGATAGCGCTACATCTGTGGGTAACTCCACCGGAACGGGAACACCAGCAGGAACGCCTATTGGAGCTACTACCTCCACCATTATTTTAAACGCTAACAACGGAACGGCAGGAGTCAGTGGAGCCGGCACCACTACAATCCTCACACAGAAATCCGGTCACACGAACTACAACATCTTCAATACCACGGCCACTGGTAGCCAAACGCCCACTACAACATTGTTAAACCGGGTGAATCTTCACCCCAAGATGAAAACCCAGCTGATGGTTAACGCCAAGAAGCTGTCGGAAGTAACGCAGACCACGGCGAAAGTGTCGATTGGCAACAAGACTATATCGGTGCCGCTGCTCAAGCCGCTGATGAGCGCTAGTGGAGCGGCCACAGCCGGAGGAGCCACGATTGTAGAGAGCAAGCAACTGCTGCAGCCGGGCGGTCAGGTGACTACCGTAATGAGTGCTGCGCAGCAAAGCGGTGGTCAGCAGGTCCACCCGCACGTCCATTCTCATGCACATCACAACTTTACCAAACTTATCAAACGCGGGCCAAAAAATAGCGGCACCATTGTCTCGTTTTCGGGGCTACAGATCAAGCCGGCGAACACCAAAATTGTGGCCACCAAGGTGGTGAGCAAAAAGATGCTGCAACTTCAGCAGCACCAACAACAGATCCAACAGCAGCAGCAGCTGCAGGTGACCAGTGGTGGAGGCCTGGCTCCGCCCACAGGCAGCATAGTGACTATCACCACCACCAACCCCAGCCAAACGTACGCAATGGTTCAGGATTCCGCAACTGTGGGACCTGCGGCCCATTCGGAAGACGATGCGCCAGCGCCTCGAAAGATTACAGCCTACTCGGAGAACCTTCAAAAAATTCTCAACAAGAGCAAGTCCCAGGAATCGACTGGAGGCCCGGAGGAGTTCACCAACATCAACAGCGTGGTGATTAAGCCGCTCGACAAGAATACACTCAATTGTCCGCCCAGCTTTAACATCTTTAAGCAGCAGCAGCACTCACAGGCTGCTCAAAGCCAATCATTCTCCGCGGTAGGCAGTGGAGCAGGCACACCCGTGACTTTTACCATGGCTTCGGGGAATGCCTCAGATCTGGCCACCACCTCCACCGTTTCCGTTTCGGCGGGGACCATCTGCATAAACAGTCCGATGATGGGCACGCGGCCAATAATCTCCATTCAGAACAAGAACATATCCCTGGTGCTGTCCAAGACGACCATGGCCCAGCAAAAACCGAAGATGATAACTACAACCACGTTGTCCAGTCAGGCGGCGCTGCAGATGCATCATGCTTTGATTCAGGATTCTAGTGCAGACAAGGCGGGATCTTCTGCAAACTCCGGATCAGCTACCTCGGGAGCTTCAATGCAGCTGAAACTAACGACCGCCAATACGCCCACCAAACTCAGCGTTAGTCTGGCTCCGGACGTAGTCAAGCTGGAAGAAGTTGGCAGCGAATCTAAAGCAAAGCTACTGGTCAAACAGGAGGCGGTTGTGAAGGATAGCACTGGTACTCCGACCAGTGAGGAGCGGGCTGAGGAGATCGGCACGCCGGAGAAGCGTTTGAACGCCAATGCCACAATGACGGCTATTAACCAGGTTCAAAATCAGTCCGCCAATCAAATTCAAATGGCCACATCTACCTCAACTGCCTCGAATCCCAGCACACCCAATCCTACAGTGAACGCCACACCTATGAACAACCAACGCTCGGCAGCGGAGGATAATGCGCTTCTAAAGCAACTGCTCCAAAACAACAGCAGCAGTCATAGCCTCAACCAGATAAGCATCACTTCGGCTCACGTTGGTTCCGCCTCAGCTTCGGCACCTCTTTCCGCCCGCAAGGTTATCAACGTACGGGCGCCCAGCATGGGGAAGGTCAGAAGTTTGGAGGATCAACTGGCACGTCCGGTGATTCCTCCGGTGCCCACTGCCACGCAGGCGGCAGGTAGTAGTAGTAGCAGTGGATCTGTGGCCACGTCCACCACCACCACAACAGTAGCTAGCGGAGGAAGCAGCCAACAGGTAGCCACCGCCTCAGCGACGGCTCTACCTGTTAGTGCGGTCGCAATTACCACACCAGGAGTGGGAGGGGAGGCAAAGCTGGAGCAGAAATCCGATCAGCCAGCAGCAATTATGCAGAATCAGAGCCAAAACCAGGCGCCTCCACCACCACCGCCACCACAGCAGCAGCGGCAGCAGCAACTACACCAGCCGCAGCAGCTGCAACCGTCACCCCACCAAGTCAAGCAGACTGTGCAGATTGTGTCGAAGGAGACGTCGTTCATCTCAGGACCCGTTGCTGCTAAAACACTAGTGACGGAAGCCACTTCGAAGCCGGCTGAACTACTACCTCCTCCGCCTTACGAAATGGCCACTGCTCCTATATCGAACGTCACCATATCCATATCCACCAAACAAGCGGCTCCGAAGGAACTGCAGATGAAGCCCAAGGCGGTAGCTATGTCACTACCCATGGAGCAGGGCGACGAATCGCTGCCAGAGCAAGCGGAGCCGCCGCTTCATTCGGAACAGGGAGCTACTGCAGCGGGAGTTGCACCTCACTCCGGAGGTCCCCTTGTGTCTGCGCAATGGACCAATAACCATTTAGAAGGAGGTGTAGCCACCACAAAGATACCGTTCAAGCCTGGAGAGCCTCAAAAACGCAAGCTCCCCATGCACCCACAACTGGACGAAAAGCAGATCCAGCAACAGGCAGAGATTCCCATAAGCACCTCCCTACCAACAACTCCGACTGGACAAGGTACTCCCGACAAGGTACAGCTGATCTCAGCGACTGCCACTTATGTAAAGAAATCCGGTGTCCCGAACGAGGCACAACCCATCCAGAACCAGAGCCAGGGCCAGGTGCAGATGCAGGCGCAAATGCAGGCGACTATGCAAGGACACCTGTCTGGGCAGATGTCCGGACAAATCTCCGGACATGCCGCTGGACAGATACCCGCTCAAATGCATTTGCAAGTACAGCATCAGCTCCATATGGCAGTTCATCCACAGCAGCAGCAGCAGCAACTGCACCAGAACCAACCACAGAATGCGACGATTCCCCTTCCGGTTACTGGACAGGGTGCAGTGCCCATCCCCGTGCCCACCATGGAGAGCAAGGCAGGCGACCAAAGGAAGCGCCGCAAACGTGAGGTCCAGAAGCCGAGGCGCACAAATCTGAACGCCGGACAAGCGGGTGGAGCTCTTAAGGATCTAACAGGTCCACTACCGGCAGGTGCAATGGTCCAACTGGCAGGAATGCCGCCGGGGACCCAGTACATACAAGGCGCGGCATCAGGGACTGGTCATGTGATCACCAGTACCGGACAAGGAGTTACTTTGGGAGGAGTGGGCGCCAGTACTGGAGCCAGTTCCTCGCCCATGCTCAAGAAGCGGGTTCGCAAGTTCTCCAAGGTAGAAGAGGATCACGATGCATTTACCGAGAAGTTGCTGACGCACATCCGCCAAATGCAGCCGCTTCAAGTTCTGGAGCCGCATCTCAATCGCAACTTTCACTTTCTTATCGGGAGCAACGAGACTTCTGGAGGTGGTTCGCCCGCCTCAATGAGTTCTGCGGCTTCTGCCGGATCATCATCGGCTGGAGGAGGAAAGCTGAAGGGCGGATCTCGAGGCTGGCCACTGAGCAGGCATTTGGAAGGTCTGGAGGACTGTGATGGCACCGTTCTCGGCCGCTATGGTCGAGTGAATCTGCCAGGGATACCCTCGTTGTACGATAGCGAACGCTTTGGCGGAAGTAGAGGTCTAGTTGGTGGATCTGCACGAACCCGTTCACCCTCGCCAGCAGTGTCTCCGGGAGCAGAAAAGATGCTACCAATGTCTAGCATCCAAAATGATTTTTATGACCAGGAGTTCTCCACGCATATGGAGCGCAATCCTAGGGAACGCCTGGTGCGGCACATTGGAGCCGTCAAGGATTGCAATTTGGAGACCGTAGACCTGGTGGAGAGCGAGGGCGTAGCTGCGTGGGCGACTCTTCCACGACTTACCCGCTATCCGGGTCTAATACTGCTCAATGGAAACAGCCGTTGCCATGGACGGATGTCGCCGGTCGCACTGCCGGAGGATCCGCTGACCATGCGCTTTCCCGTGTCTCCACTGCTTCGATCCTGCGGCGAAGAGCTGCGCAAGACACAGCAGATGGAGCTGGGAATGGGACCGCTGGGCAATAATAATAATAACAATTACCAGCAGAAGAACCAGAATGTGATACTCGCACTGCCCGCCTCGGCATCGGAGAACATAGCCGGCGTGCTGCGGGATCTGGCCAATCTACTGCACTTGGCGCCCGCCCTTACCTACAAGATCATCGAGGACAAGATTGGCAACAAGTTGGAGGACCAGTTTATGAATCAGGACGATGAAAAGCACGTCGACTTCAAGCGACCACTGAGTCAAGTGAGTCACGGTCATCTGAGGAAGATCCTCAACGGGCGTCGTAAGCTCTGCCGCAGCTGCGGAAATGTGGTTCACGCCACTGGGCTGCGAGTTCCTCGGCACAGTGTTCCTGCCCTAGAAGAGCAACTCCCCCGGTTGGCTCAACTGATGGACATGCTGCCAAGAAAATCGGTTCCCCCTCCTTTTGTGTACTTCTGCGATCGCGCCTGCTTTGCGAGATTCAAGTGGAATGGAAAGGATGGCCAGGCGGAGGCGGCTAGTCTGCTGCTTCAGCCAGCCGGCGGTTCTGCTGTAAAATCATCCAACGGAGACTCGCCTGGCAGCTTCTGCGCCAGCTCAACTGCCCCAGCGGAAATGGTGGTCAAACAAGAACCGGAGGACGAGGATGAGAAAACGCCGAGCGTACCGGGCAACCCCACAAATATCCCCGCACAGCGCAAATGCATTGTGAAGTGTTTTAGTGCTGATTGCTTCACCACGGACTCGGCGCCATCCGGACTGGAGCTCGACGGAACTGCTGGTGCCGGAACTGGGGCTGGACCGGTCAATAATACTGTGTGGGAAACAGAGACCAGTGGGCTGCAGTTGGAGGACACGCGGCAGTGTGTCTTCTGCAATCAGCGTGGTGACGGCCAGGCAGATGGACCCTCGCGACTGCTTAACTTCGATGTGGATAAATGGGTTCACCTTAACTGCGCCCTGTGGTCCAACGGCGTGTACGAGACAGTGTCTGGGGCGCTGATGAACTTCCAGACAGCTCTGCAAGCGGGACTGAGCCAGGCGTGTAGCGCTTGTCACCAACCAGGCGCCACCATCAAGTGTTTCAAGTCGCGCTGCAACAGCCTGTACCACCTGCCATGCGCCATTCGCGAGGAGTGCGTCTTTTACAAGAACAAGTCCGTGCACTGCAGCGTTCATGGTCATGCTCATGCCGGCATCACGATGGGTGCAGGAGCAGGCGCCACGACTGGCGCCGGATTAGGAGGCTCTGTGGCAGATAATGAACTGAGCTCCCTGGTTGTCCACCGGAGAGTTTTTGTCGATCGGGATGAAAACCGTCAGGTGGCCACCGTCATGCACTATTCAGAGCTAAGCAACCTGCTCCGTGTGGGCAACATGACGTTCCTGAACGTGGGTCAGTTACTGCCGCATCAGCTGGAGGCCTTCCACACACCCCACTACATCTACCCCATTGGCTACAAGGTGAGTCGCTACTACTGGTGCGTGCGACGACCCAATCGTAGGTGTCGATACATTTGCAGTATCGCAGAGGCCGGATGCAAGCCCGAGTTTCGCATCCAGGTGCAGGACGCCGGCGACAAGGAGCCGGAGCGCGAGTTTCGGGGCAGTTCGCCCTCGGCGGTCTGGCAGCAGATTCTGCAGCCAATCACGCGACTGCGTAAGGTGCACAAGTGGTTGCAGCTCTTTCCCCAGCACATCAGTGGTGAGGACCTATTTGGCCTAACGGAACCGGCCATTGTGCGAATCCTGGAAAGCCTCCCGGGCATTGAGACGCTCACTGACTACCGCTTCAAGTACGGTCGCAACCCGCTTCTTGAGTTCCCGCTAGCCATCAATCCGTCTGGAGCGGCGCGTACGGAACCCAAGCAACGACAGCTGCTCGTCTGGAGGAAGCCGCATACGCAACGCACGGCCGGCAGCTGCAGCACGCAGCGGATGGCCAACTCGGCTGCGATTGCCGGAGAAGTGGCCTGCCCGTACAGCAAGCAGTTCGTGCATTCGAAGAGCTCCCAGTACAAAAAGATGAAGCAGGAGTGGCGCAACAACGTCTACTTGGCGAGATCTAAGATCCAGGGTCTTGGCTTGTATGCAGCTCGGGACATTGAAAAGCACACCATGATAATCGAGTACATTGGCGAGGTTATCCGCACCGAGGTCTCCGAGATACGCGAGAAGCAGTACGAGTCCAAGAACCGTGGCATCTACATGTTCCGGCTGGATGAAGACCGCGTGGTGGACGCCACTCTAAGCGGCGGGTTGGCGCGCTACATCAACCATTCGTGCAATCCCAACTGTGTTACCGAGATAGTGGAGGTCGATCGCGACGTGCGGATCATAATATTCGCCAAGCGGAAGATCTATCGCGGCGAGGAGCTCTCGTACGACTACAAGTTCGACATTGAGGACGAGTCGCACAAGATACCGTGCGCCTGTGGAGCGCCCAACTGTCGCAAGTGGATGAAC

CDS AA Sequence²

MNIPKVTTSLGAAEKAKPERVASVAAAAFNAVSLQKRSGDDTATPAEDPTRKKAKTELLFGTGTAAPSLPAKASSTAPQQLLYQRSGQQAKAQVKAASEPQDVETADGVWDARDQQIIVCNFGSGTEMGAIKAEDADKQTFTSFTKKEGASSSASSSSSTASVISIEPSGSGQDHAENSGKSEDLDYVLMPASGADSATSVGNSTGTGTPAGTPIGATTSTIILNANNGTAGVSGAGTTTILTQKSGHTNYNIFNTTATGSQTPTTTLLNRVNLHPKMKTQLMVNAKKLSEVTQTTAKVSIGNKTISVPLLKPLMSASGAATAGGATIVESKQLLQPGGQVTTVMSAAQQSGGQQVHPHVHSHAHHNFTKLIKRGPKNSGTIVSFSGLQIKPANTKIVATKVVSKKMLQLQQHQQQIQQQQQLQVTSGGGLAPPTGSIVTITTTNPSQTYAMVQDSATVGPAAHSEDDAPAPRKITAYSENLQKILNKSKSQESTGGPEEFTNINSVVIKPLDKNTLNCPPSFNIFKQQQHSQAAQSQSFSAVGSGAGTPVTFTMASGNASDLATTSTVSVSAGTICINSPMMGTRPIISIQNKNISLVLSKTTMAQQKPKMITTTTLSSQAALQMHHALIQDSSADKAGSSANSGSATSGASMQLKLTTANTPTKLSVSLAPDVVKLEEVGSESKAKLLVKQEAVVKDSTGTPTSEERAEEIGTPEKRLNANATMTAINQVQNQSANQIQMATSTSTASNPSTPNPTVNATPMNNQRSAAEDNALLKQLLQNNSSSHSLNQISITSAHVGSASASAPLSARKVINVRAPSMGKVRSLEDQLARPVIPPVPTATQAAGSSSSSGSVATSTTTTTVASGGSSQQVATASATALPVSAVAITTPGVGGEAKLEQKSDQPAAIMQNQSQNQAPPPPPPPQQQRQQQLHQPQQLQPSPHQVKQTVQIVSKETSFISGPVAAKTLVTEATSKPAELLPPPPYEMATAPISNVTISISTKQAAPKELQMKPKAVAMSLPMEQGDESLPEQAEPPLHSEQGATAAGVAPHSGGPLVSAQWTNNHLEGGVATTKIPFKPGEPQKRKLPMHPQLDEKQIQQQAEIPISTSLPTTPTGQGTPDKVQLISATATYVKKSGVPNEAQPIQNQSQGQVQMQAQMQATMQGHLSGQMSGQISGHAAGQIPAQMHLQVQHQLHMAVHPQQQQQQLHQNQPQNATIPLPVTGQGAVPIPVPTMESKAGDQRKRRKREVQKPRRTNLNAGQAGGALKDLTGPLPAGAMVQLAGMPPGTQYIQGAASGTGHVITSTGQGVTLGGVGASTGASSSPMLKKRVRKFSKVEEDHDAFTEKLLTHIRQMQPLQVLEPHLNRNFHFLIGSNETSGGGSPASMSSAASAGSSSAGGGKLKGGSRGWPLSRHLEGLEDCDGTVLGRYGRVNLPGIPSLYDSERFGGSRGLVGGSARTRSPSPAVSPGAEKMLPMSSIQNDFYDQEFSTHMERNPRERLVRHIGAVKDCNLETVDLVESEGVAAWATLPRLTRYPGLILLNGNSRCHGRMSPVALPEDPLTMRFPVSPLLRSCGEELRKTQQMELGMGPLGNNNNNNYQQKNQNVILALPASASENIAGVLRDLANLLHLAPALTYKIIEDKIGNKLEDQFMNQDDEKHVDFKRPLSQVSHGHLRKILNGRRKLCRSCGNVVHATGLRVPRHSVPALEEQLPRLAQLMDMLPRKSVPPPFVYFCDRACFARFKWNGKDGQAEAASLLLQPAGGSAVKSSNGDSPGSFCASSTAPAEMVVKQEPEDEDEKTPSVPGNPTNIPAQRKCIVKCFSADCFTTDSAPSGLELDGTAGAGTGAGPVNNTVWETETSGLQLEDTRQCVFCNQRGDGQADGPSRLLNFDVDKWVHLNCALWSNGVYETVSGALMNFQTALQAGLSQACSACHQPGATIKCFKSRCNSLYHLPCAIREECVFYKNKSVHCSVHGHAHAGITMGAGAGATTGAGLGGSVADNELSSLVVHRRVFVDRDENRQVATVMHYSELSNLLRVGNMTFLNVGQLLPHQLEAFHTPHYIYPIGYKVSRYYWCVRRPNRRCRYICSIAEAGCKPEFRIQVQDAGDKEPEREFRGSSPSAVWQQILQPITRLRKVHKWLQLFPQHISGEDLFGLTEPAIVRILESLPGIETLTDYRFKYGRNPLLEFPLAINPSGAARTEPKQRQLLVWRKPHTQRTAGSCSTQRMANSAAIAGEVACPYSKQFVHSKSSQYKKMKQEWRNNVYLARSKIQGLGLYAARDIEKHTMIIEYIGEVIRTEVSEIREKQYESKNRGIYMFRLDEDRVVDATLSGGLARYINHSCNPNCVTEIVEVDRDVRIIIFAKRKIYRGEELSYDYKFDIEDESHKIPCACGAPNCRKWMN

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.