Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
NC2beta (FBgn0028926)	cofactor	(-0.39/-2.12/0.45)	4	◼	◻	◻	◻	◻

Factor activity

Celltype:
S2

Additional information

NC2beta [FlyBase] | NC2beta [FlyMine] | NC2beta [BDGP]

H. sapiens orthologues¹

DR1 (HGNC:3017, ENSG00000117505)

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
CG6470	1.448 (1)
CG11317	1.451 (2)
CG15715	1.476 (3)
RunxB	1.500 (4)
Crg-1	1.527 (5)

All TFs

Cofactor	Euclidean distance (rank)
CG17446	1.054 (1)
TfIIA-S-2	1.194 (2)
Cp1	1.266 (3)
san	1.318 (4)
Prosalpha7	1.319 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
Crg-1	0.916 (1)
Rel	0.909 (2)
CG11317	0.902 (3)
RunxB	0.900 (4)
fd68A	0.897 (5)

All TFs.

Cofactor	Pearson correlation (rank)
Rpn3	0.975 (1)
CG6154	0.974 (2)
TfIIA-S	0.969 (3)
TfIIEbeta	0.966 (4)
CG33502	0.966 (5)

All cofactors.

CDS DNA Sequence²

ATGTCGAATCCGCAGGAAGAACTACTGCCGCCCAGCGCCGAGGACGACGAGCTGACCCTGCCACGGGCCAGCATCAACAAGATCATCAAGGAGCTGGTGCCCACGGTGCGGGTGGCCAACGAGAGTCGCGAGCTGATACTCAACTGCTGCTCAGAGTTCATTCATCTGATCAGTTCGGAGGCCAACGAGGTGTGCAACATGCGCAACAAGAAGACGATAAACGCAGAGCACGTCCTGGAGGCGTTGGAACGCTTGGGTTTTCACGACTACAAACAAGAGGCGGAGGCCGTTCTGCACGACTGCAAGGAGGTGGCAGCCAAGCGAAGGCGCCAGAGCACGCGCCTAGAGAACCTGGGCATTCCGGAGGAGGAGCTGCTGCGCCAGCAGCAGGAGCTGTTCGCCAAGGCACGCGAGGAGCAGGCGCGCGAGGAGCAGCAGCAGTGGATGAGCATGCAAGCGGCAGCAATGGTGCAGCGACCACCGCTGGCAGACGGCTCCGTTGCCAGCAAGCCAAGTGAGGATGGCGATGACGATGACGACGACGACTAC

CDS AA Sequence²

MSNPQEELLPPSAEDDELTLPRASINKIIKELVPTVRVANESRELILNCCSEFIHLISSEANEVCNMRNKKTINAEHVLEALERLGFHDYKQEAEAVLHDCKEVAAKRRRQSTRLENLGIPEEELLRQQQELFAKAREEQAREEQQQWMSMQAAAMVQRPPLADGSVASKPSEDGDDDDDDDY

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.