Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
Ptx1 (FBgn0020912) TF
 
(-0.15/-1.41/1.22)

Factor activity

Additional information

Ptx1 [FlyBase] | Ptx1 [FlyMine] | Ptx1 [BDGP]

H. sapiens orthologues1

PITX2 (HGNC:9005, ENSG00000164093), PITX1 (HGNC:9004, ENSG00000069011), PITX3 (HGNC:9006, ENSG00000107859)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGGACCGCTCCTCCGCCGTCGGCGGTTGCGGCGGGGGCGGCGGTCTGGGAGTGGGCGTGGTCACCAGCTCGGCCACGGCCTTGGGACCGGGTGGCCTGACCAACGGGGGCGGCGGAGTGGTCAGTGGCGCACTCAACGGATTGGAGGCCATGTCGGCCGAGTCCACGGGTCTGTGCCTGCAGGATCTGGTGAGTGCCGGGACGGCCAACGGAGCAGGCTCCGCAGGATCGGCAGAGAGTGCCACCACCACCAGCACGGCACTGAGCAGCGGCAGCACCGGAAGCTCCACGGTCAACGGAGGAGGCAGCAGCACCTCCGGCACGGAGCACCTGCACAGCCACCACAGCCTGCACGACTCCAGCTCGTCGGTCAGCATCTCACCCGCCATCTCGAGCCTGATGCCCATCAGCAGCCTGAGCCACTTGCACCACTCCGCGGGCCAGGACCTGGTGGGTGGCTACTCCCAGCACCCGCATCACACGGTGGTGCCGCCGCACACGCCCAAGCACGAGCCGCTCGAGAAACTCAGAATTTGGGCCGAAACCGGCGATTTCCGTGATAGTCATAGCTCCATGACCGCCGTAGCAAATAGTTTGGATAGCACCCACTTGAACAACTTTCAGACGTCATCGACATCCTCGATATCGAACCGGAGTCGGGATCGCAAAGATGGCAATCGCAGTGTAAACGAAACCACGATCAAGACAGAAAACATATCAAGTTCCGGGCACGATGAGCCGATGACCACCAGTGGCGAGGAGCCGAAGAACGACAAGAAGAACAAGAGGCAGCGGCGCCAGAGGACACACTTCACCTCGCAACAGCTCCAGGAGCTGGAGCACACCTTCAGCCGGAACAGGTATCCGGACATGTCCACCCGCGAAGAGATCGCCATGTGGACCAATCTTACAGAGGCCCGCGTCAGGGTGTGGTTCAAGAATCGGCGGGCCAAGTGGCGCAAGAGGGAGCGGAACGCGATGAACGCGGCAGTGGCGGCGGCGGACTTTAAGTCCGGATTCGGAACGCAGTTCATGCAGCCGTTCGCGGATGACTCGCTGTACAGCTCGTATCCGTATAACAACTGGACCAAGGTGCCCTCGCCGCTGGGAACCAAGCCCTTTCCGTGGCCAGTGAACCCACTCGGATCGATGGTGGCCGGCAATCATCACCAGAACTCGGTGAACTGCTTCAACACGGGCGCCAGTGGCGTGGCGGTCAGCATGAACAACGCATCCATGCTGCCGGGTTCGATGGGCTCGTCCTTGAGCAACACCAGCAACGTGGGAGCCGTGGGCGCCCCCTGTCCGTACACCACCCCCGCCAATCCGTACATGTACCGCTCCGCCGCCGAGCCCTGCATGAGCAGCAGCATGAGCTCGAGCATTGCCACCCTGCGGCTGAAGGCTAAGCAGCACGCCTCCGCCGGATTCGGCAGCCCCTACTCCGCCCCCTCCCCCGTGTCGAGGTCCAATTCCGCCGGACTCTCCGCCTGCCAGTACACCGGAGTGGGCGTGACGGACGTGGTC

CDS AA Sequence2

MDRSSAVGGCGGGGGLGVGVVTSSATALGPGGLTNGGGGVVSGALNGLEAMSAESTGLCLQDLVSAGTANGAGSAGSAESATTTSTALSSGSTGSSTVNGGGSSTSGTEHLHSHHSLHDSSSSVSISPAISSLMPISSLSHLHHSAGQDLVGGYSQHPHHTVVPPHTPKHEPLEKLRIWAETGDFRDSHSSMTAVANSLDSTHLNNFQTSSTSSISNRSRDRKDGNRSVNETTIKTENISSSGHDEPMTTSGEEPKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRERNAMNAAVAAADFKSGFGTQFMQPFADDSLYSSYPYNNWTKVPSPLGTKPFPWPVNPLGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSNTSNVGAVGAPCPYTTPANPYMYRSAAEPCMSSSMSSSIATLRLKAKQHASAGFGSPYSAPSPVSRSNSAGLSACQYTGVGVTDVV

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.