Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
CG9784 (FBgn0030761)	cofactor	(-0.21/-1.65/0.37)	6	◼	◻	◻	◻	◻

Factor activity

Celltype:
S2

Additional information

CG9784 [FlyBase] | CG9784 [FlyMine] | CG9784 [BDGP]

H. sapiens orthologues¹

INPP5K (HGNC:33882, ENSG00000132376)

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
Mtp	1.173 (1)
Met	1.283 (2)
bun	1.287 (3)
term	1.405 (4)
Crg-1	1.410 (5)

All TFs

Cofactor	Euclidean distance (rank)
RpLP2	0.724 (1)
Ada	1.070 (2)
CG8117	1.080 (3)
Art7	1.152 (4)
Nurf-38	1.230 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
l(2)k10201	0.899 (1)
Mtp	0.885 (2)
Met	0.868 (3)
bun	0.857 (4)
Crg-1	0.836 (5)

All TFs.

Cofactor	Pearson correlation (rank)
PSR	0.973 (1)
RpLP2	0.963 (2)
Nurf-38	0.949 (3)
ari-2	0.945 (4)
Ada	0.943 (5)

All cofactors.

CDS DNA Sequence²

ATGAGCCAAACGGAGGCTAGCAAGACACCCAAGATTCCGGACTCGGAGCCGGACGGATCGAAGGGCAAAGGGAAGCAACAGCTGGAAACTTACCGGGTATATGTGGTCACCTGGAATGTGGGCAGTCGATTTCCGGATAACATATCCCTCCGCCATCTGCTGGGACTGCAGGATGTGACGGTGGATAAGGACACGAAGGAGACTAATGCCCACTTGCCGGACATCTATGCGTTGGGGCTCCAGGAGGTCAATGCCCAGCCGCAGCAACAGGTGTTGGGACTGTTCAAGGAGGATCCGTGGACGCACAAGGCTAAGGAACTGCTACGCAACTACGACTATGTGGCCGTAAAGACCGAGCAGATGCAGGGGCTGCTGCTCAGCATGTTCGTGAGGCGGCAGCACGTTGAGCACTTGCAGGACATCGAGGCGGAGTTCACGAGGACCGGTTTCGGTGGCATTTGGGGCAACAAGGGCGCCGTCAGTGTCAGGTTCACCCTTTACGGCTGCGGACTGGCCTTTGTGGTGGCCCATCTGACTGCCCATGACCATATGATGGACGAGCGCATCGAGGACTACAAGCAGATACTGGAGAACCATCACTACCACGTCAAGCGGTATAGGGAGATCTACGATCACGACTATGTCTTCTGGTTTGGCGATCTGAACTTCCGACTGCAGGGCAGCGATTCCTCGACGGAAGTGCGCGAGTTGGTACGCGATGAGTCCCAGCACGAGGCCCTTATCCAGCGGGATCAATTGTATCAAGTTCGCGAGAAGTCGCAGCTGGCCTTTCAGGTTCTGCAGGAGCGACTGCCCGCCTTTCCGCCCACCTTCAAGTTCCGCGAGGGCACCTCCGAGTACGACCTGAAGCGGCGGCCAGCCTGGACGGATCGGATAATGTACGCCGTGCAGCCACTGAACCGGCAGCCCGGCATGCAGCTATCCATTGAGCAATGCTCGTATAAGTCCCATCCCCTGTACACCATCAGTGATCACAAGCCGGTGACCAGTGACTTTACCATCAAGCTCTACCCGAATGTACGGGCGCCCGGCGTGGTGTTCTCGCCTCTGTCGCTCTGGAAGATTGGGGACGAGAACACGGTGGAGTATCACAAGCAGGCAGAGTTCGACGAGGGGTCCAACGACTGGATTGGCATCTTTCCGTCGGAGTACGCCAGTTTGGCGGATTACGTAGCCTACGAGTATGTCAATCAGGCTGAGTCGCCCTCATCCTCGGACTCCAATCACCAACCGGATCCGTTTGAGACGCCCTCGCATCATCGAAGGGGTCGGCATCATCACAGGAATCGCCAGCGACAGCGTCGCCATCAGGAGGCTAATGCCCAAGAGTTGGTGCGGCTAGATTTCGCCGACGATGTGGAACTGCGTCACGGCGAGCAATACCTGTTGATATATTTCCGCAGCACCGGAGTCCGGGGCGTGACCAGTTTGGCCGGCGTCAGTGGTGTCTTTGTGGCGGAGAAGCGGCACGGCTCGCCCCATCGGACGGAGTACCATGTTGAC

CDS AA Sequence²

MSQTEASKTPKIPDSEPDGSKGKGKQQLETYRVYVVTWNVGSRFPDNISLRHLLGLQDVTVDKDTKETNAHLPDIYALGLQEVNAQPQQQVLGLFKEDPWTHKAKELLRNYDYVAVKTEQMQGLLLSMFVRRQHVEHLQDIEAEFTRTGFGGIWGNKGAVSVRFTLYGCGLAFVVAHLTAHDHMMDERIEDYKQILENHHYHVKRYREIYDHDYVFWFGDLNFRLQGSDSSTEVRELVRDESQHEALIQRDQLYQVREKSQLAFQVLQERLPAFPPTFKFREGTSEYDLKRRPAWTDRIMYAVQPLNRQPGMQLSIEQCSYKSHPLYTISDHKPVTSDFTIKLYPNVRAPGVVFSPLSLWKIGDENTVEYHKQAEFDEGSNDWIGIFPSEYASLADYVAYEYVNQAESPSSSDSNHQPDPFETPSHHRRGRHHHRNRQRQRRHQEANAQELVRLDFADDVELRHGEQYLLIYFRSTGVRGVTSLAGVSGVFVAEKRHGSPHRTEYHVD

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.