Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
CG10445 (FBgn0037531)	cofactor	(-1.04/-3.80/-0.31)	13	◼	◻	◻	◻	◻

Factor activity

Celltype:
S2

Additional information

CG10445 [FlyBase] | CG10445 [FlyMine] | CG10445 [BDGP]

H. sapiens orthologues¹

None.

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
mor	1.514 (1)
srp	2.304 (2)
Rel	2.338 (3)
BEAF-32	2.437 (4)
CG9609	2.531 (5)

All TFs

Cofactor	Euclidean distance (rank)
SuUR	0.839 (1)
Orc2	0.892 (2)
Parg	0.948 (3)
Su(var)3-9	1.255 (4)
TfIIFalpha	1.432 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
Mtp	0.959 (1)
Met	0.933 (2)
Crg-1	0.919 (3)
CG33936	0.917 (4)
mor	0.915 (5)

All TFs.

Cofactor	Pearson correlation (rank)
CG6805	0.986 (1)
CG31730	0.982 (2)
Su(var)3-9	0.981 (3)
Elp3	0.981 (4)
CG9426	0.981 (5)

All cofactors.

CDS DNA Sequence²

ATGGAATCATCTTCACCATCAGATACAACCGAAATCCACAAACAATCGTGCAGCATTCAAGACCAGAGCAGCGTCCCCGTGCCGGACAGCTCTGGTGAAATTAACAACTGGATGGAGCCTGAGCCAGTTGACAGTCTCGAATTGTCAGGTGAATATGCCGACAATGAAAGTGCAATTTTTGTCAGTGCTTCGGAGTATAACGAAAAAAAAGCACAGATCGATCAGCTGGTGCAAAAGATACTCACAATGGAGCAGCAGCAGCGGCAACTGGAGGAGAACGCGTCCGAAACCAAGGAGCTTTGCGATTTAAAGTTGCACCTGGAGAAGCTCAATGCCCGCCTGGAGGCGCTGGGCGAATTCCTGGACACTTTGCGTTTGTGGGAGGACCAGCAGGAGATCAAAATCGAAGATAACTCGGAACTGGTGGACCACACCGAGCAGCCCAAGTGGAGCAATTTGTACTCCGGTCTGAACCGCTATCGACAAAAGGCCAACCACACTGCAGCGCAGTTCTATCAGCACAAGAGCAACATAATCGACAGTCTGAAGACCCTGTATGAGCCCATTCAGCCACGTCCTGCAATCGATGACTTGGAAAAGCAACCCGCTTTGCTGTTAGTGCGCCTGCTAAAGCATCAGCAGTCTTGCTTGAAATGGATGCAATTTCGTGAGCGTCAGAAGATCTCTGGAGGAATCCTTGCCGACGACATGGGCCTTGGAAAAACTCTATCTATGATAGCCCTAATCTTGGCTTCGGAAGAAACTAAGAACAGAAAACGAGAAGAAAAGAAGAAAGCCTTGACGTTAAAGTGGACTCAGGAGTTTAATCGAGTATATTGTAAGGAAATCCGTAAAATCAGCATGTTTGATGATGAAGAAGAGTCTGGAAAGGAGGAGGAGCAGTACGAGCCGCCGGAGAAGCGCACCTGTCACGTGAAGACTAAAAAAATCAATCAATTTCGAATTTTGGATGATGATGATAATGATGCCGGAGACAAAGCTGTAGTGGAGGATGAACAGAAAGATCTGCTAGCAAAGACTCCCGAACCAGAGGTTTTCAGTTCGGATGAAGAGGAGGAGCACTTATCAAACGGCCGCTATCCCTCGGCAAACACATTAGTTGTTTGCCCCATGAGCGTTATGTGTCAGTGGGCCCATGAGGTGGCCTCCAAGGTAGCGCAAAATGCCATTAGGGTGCTGACTTTTCACGGACCCAATCGCCATGAAATCGGAATAGAGGCATTCAGGAGCTATGATTTAGTCATTACCTCGTATAATCTCGTAGTAAACGAGCTTAAACGATATGGAAACACTTCTCCACTGTTCGCCGTGTACTGGAACCGCGTGATCCTCGACGAAGCTCACATCATTCGGAATTCTAAAACCAACTGCTGTAACTCTGTATGCCAGTTGCGGGCGCATTGTCATTGGGCCCTGACTGGAACGCCTGTCCAGAATCGGGGCGTCGATGTGTTCGCCCTGCTGCGGTTTGTAAATGTACCAAACTTTCAGGACCTCCAGCAGTGGAAAAAGAACCTAAACGAAAGCATGCTCGGACATCGCCGACTTAACTTTATAATAAAACCACTAATGCTGCGCAGGACAAAGCAAAAGCTACAGGCATCTGGCGACATGCCTGCGCTGCCTTCCCTTAAGATTGAACTTATATGCGTACAGCTATCGAAAACTGAAATGGCCGTGTACCAGATCCTGTCTGCCATATCCAAAAAAATCTTTACACAGTTCCTGCTCCAACGCGAGAAGGGCAACAGTGATTTAAATTATTACTCTCTGGAAAGAACCCCACAGTTTATAGCCGGACATATGTCCGACGAAAGGTACAACGAGATCTACGAAAGATTCCTTAAGTCGCTTGGCTACAATCCAGGGGAAAAGATCCTTGGTATCTATATCCTGGTGCTACTGCTGCGGCTACGACAGTTTTGTTGCCATCCGGGACTAATGATTGGGATGCTGCGTGGTGCTTTGACCGCCGAGGACGTCCAGAACGTGAAGGTGGATGCCTCAGACGTGGAGGGCCAGCTCAAGATGGATGTCCTTGCCGAGTTGGATAAGTTTGACGAAACCGATAGCGAAGATGACTGTTGTGACGAGGAGGACAGTACTAGAAGAGATGGCAATTTCAAGTTGGAAGTGATAAAAGATGAAATTAAGGAGGAGAATGTGCCATGGGATTCTGGTGATGACCTGCCAACGGCCAGTTCTTTTGAGGATCAACTAGATAGTGCCAGAGCTCTTAAACTGCTCAATCCCCAGAATCCCATCTTTCAGTTCATACGCCCTTCTGCCAAACTAAAGATGGTCATTGATAAGCTAGAGGAACTGCTCACAGGCACCAACGACAAAATCATTGTTACATCTCAGTGGGTAAGCTATCTCGCAATCGTCCGTAAAAGACTGCAGGATCTATCATGGGAAACACTTGACTTTAATGGCCAGCTGACCGCCAAAGAACGCGAGATTGTACTGCGAGACTTTAACGCGAATAACGAGAAGCGCGTTCTTCTACTCTCCCTCACCGCTGGCGGAGTGGGACTGAATCTGAACGTGGCCAATCATATGCTAATTGTGGACCTCCACTGGAACCCGCAGCTGGAGCGACAGGCTCAGGACCGCATTTATCGATATGGTCAAACTAAGCCTACCTTCATCTACCGCTACATGTGCCAGGACACTGTAGAGCAACGAATTAAGTCCCTGCAAGATTGCAAGCTAGAAATTGCGAAAGTTGTGCTTCCAGAGGAAGGAGGAGAAGTGACCAAATGTGTTGGCGGTGGTCTCAACCTCGCGGAGCTAAAGAAACTCTTCGAGATG

CDS AA Sequence²

MESSSPSDTTEIHKQSCSIQDQSSVPVPDSSGEINNWMEPEPVDSLELSGEYADNESAIFVSASEYNEKKAQIDQLVQKILTMEQQQRQLEENASETKELCDLKLHLEKLNARLEALGEFLDTLRLWEDQQEIKIEDNSELVDHTEQPKWSNLYSGLNRYRQKANHTAAQFYQHKSNIIDSLKTLYEPIQPRPAIDDLEKQPALLLVRLLKHQQSCLKWMQFRERQKISGGILADDMGLGKTLSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKISMFDDEEESGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKTPEPEVFSSDEEEEHLSNGRYPSANTLVVCPMSVMCQWAHEVASKVAQNAIRVLTFHGPNRHEIGIEAFRSYDLVITSYNLVVNELKRYGNTSPLFAVYWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNFQDLQQWKKNLNESMLGHRRLNFIIKPLMLRRTKQKLQASGDMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKEENVPWDSGDDLPTASSFEDQLDSARALKLLNPQNPIFQFIRPSAKLKMVIDKLEELLTGTNDKIIVTSQWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDFNANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVLPEEGGEVTKCVGGGLNLAELKKLFEM

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.