Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
Orc2 (FBgn0015270) cofactor
 
(-0.94/-3.68/-0.25)

Factor activity

Additional information

Orc2 [FlyBase] | Orc2 [FlyMine] | Orc2 [BDGP]

H. sapiens orthologues1

ORC2 (HGNC:8488, ENSG00000115942)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGAGTGCCAGCAACAAAGGCGGTTACAAGACGCCGCGGAAGGAGAACCTCATGTCCATTGAGAACCTCACCAATTCGGAGGAGGAATCCGAGGACTTGAACACGGCAATGGTTGGGAATGCAGTGGAATCTCAGCCCAAGGTCACCAGTCGGCGTTCCACCCGACGTCCAAGTCCCACCAAGAAATACCAGGCGTACCAGAAGGAAAGCAATGGAAAAGGCCAGGAAGAGCGAATTGTTGTGAACTATGTGGAAATGTCCGATGAACGGAGCAGCGATGCGGAGGATCAGGAAGAAGAAGAAAGCATCGAGGAGTCGGAAAATGCTGCCCGTCCCGCTGCCAAGGATCTGCATCTCATCCAATCCGAGTACAATGTGGCCGGCACCAGCATGTTTGGCTTCAATACGCCCAAGAAACGCGATGCCATGGCACTGGCCGCCCTAAATGCCACGCCCTGCACGCCCAAGACCCCAAAAACGCCGCGTTTGGGTGTCAAGACGCCGGATACGAAGCGCAAGAAGTCCATGGATCAGCCAAAGACTCCCGCCCATGTGCGCACCCGCGTCAAGAAGCAGATTGCCAAAATAGTGGCCGACTCAGATGAGGATTTTTCTGGAGATGAAAGCGATTTCCGGCCCAGTGACGAGGAATCCTCCTCCAGCAGCAGTAGCAGCGATGCTGGCAACTCCTCTGACAACGACGCCGCCGATGATGAGCCCAAAACGCCCAGTAGAGCCCGCCGTGCCATTGTAGTCCCCGTTCTGCCGAAAACTCCATCGGCAGCCCGCCTGCGACAATCGGCGAGGGCGAAAAAATCGAATGAGTTTGTGCCCGAGAGCGATGGTTACTTTCACTCGCATGCCAGCAGCAAGATCCTCACTTCGGATCACACCTTGGATCGCCTAAAGAATCCTCGCCTGGCCGCCGATCGTGTTTTCAGTTTGCTGTCGGAAATCAAGACATCGGCGGAGCATGAGGGTTCTATTAATGCCATTATGGAGGAGTATCGATCGTACTTTCCCAAGTGGATGTGTATTCTGAACGAAGGCTTCAATATACTTCTATATGGATTGGGCTCCAAGCACCAGCTGCTGCAGTCATTCCATCGGGAAGTTTTGCATAAGCAAACGGTATTGGTGGTGAATGGCTTCTTTCCCAGTCTGACCATCAAGGATATGCTGGATAGCATCACAAGCGACATATTAGATGCGGGCATTAGTCCGGCTAATCCACATGAAGCAGTGGATATGATCGAGGAGGAGTTCGCACTGATACCGGAAACACATTTGTTCTTAATCGTCCATAATCTGGATGGAGCCATGCTTCGCAATGTGAAGGCACAGGCGATTCTTTCGCGCCTGGCGCGCATACCGAACATTCATCTACTGGCCTCCATTGATCACATAAATACCCCACTGTTGTGGGACCAGGGAAAGCTGTGCAGCTTCAACTTCTCGTGGTGGGACTGCACAACAATGCTGCCATATACGAACGAAACTGCGTTCGAGAACTCGCTGCTGGTGCAGAATTCCGGCGAATTGGCCCTCTCCTCGATGCGCAGTGTCTTCTCATCGCTAACGACCAATTCGCGTGGCATTTACATGCTGATTGTTAAGTATCAATTGAAGAACAAGGGCAATGCCACATACCAGGGCATGCCGTTCAGGGATCTCTATTCGAGTTGTCGCGAAGCATTTTTGGTCAGCTCAGATCTGGCACTGCGTGCCCAGCTCACCGAGTTCCTCGACCACAAGCTGGTCAAATCGAAACGGAGCGTTGATGGCTCCGAACAGCTAACCATTCCCATTGATGGCGCACTGCTGCAGCAGTTTCTCGAGGAGCAGGAGAAGAAA

CDS AA Sequence2

MSASNKGGYKTPRKENLMSIENLTNSEEESEDLNTAMVGNAVESQPKVTSRRSTRRPSPTKKYQAYQKESNGKGQEERIVVNYVEMSDERSSDAEDQEEEESIEESENAARPAAKDLHLIQSEYNVAGTSMFGFNTPKKRDAMALAALNATPCTPKTPKTPRLGVKTPDTKRKKSMDQPKTPAHVRTRVKKQIAKIVADSDEDFSGDESDFRPSDEESSSSSSSSDAGNSSDNDAADDEPKTPSRARRAIVVPVLPKTPSAARLRQSARAKKSNEFVPESDGYFHSHASSKILTSDHTLDRLKNPRLAADRVFSLLSEIKTSAEHEGSINAIMEEYRSYFPKWMCILNEGFNILLYGLGSKHQLLQSFHREVLHKQTVLVVNGFFPSLTIKDMLDSITSDILDAGISPANPHEAVDMIEEEFALIPETHLFLIVHNLDGAMLRNVKAQAILSRLARIPNIHLLASIDHINTPLLWDQGKLCSFNFSWWDCTTMLPYTNETAFENSLLVQNSGELALSSMRSVFSSLTTNSRGIYMLIVKYQLKNKGNATYQGMPFRDLYSSCREAFLVSSDLALRAQLTEFLDHKLVKSKRSVDGSEQLTIPIDGALLQQFLEEQEKK

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.