Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
CtBP (FBgn0020496)	cofactor	(-1.32/-4.36/-0.24)	7	◼	◼	◼	◼	◼

Factor activity

Celltype:
S2
Kc167
BG3
OSC
HeLa

Additional information

CtBP [FlyBase] | CtBP [FlyMine] | CtBP [BDGP]

H. sapiens orthologues¹

CTBP2 (HGNC:2495, ENSG00000175029), CTBP1 (HGNC:2494, ENSG00000159692)

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
CG15269	1.021 (1)
NK7.1	1.086 (2)
CG16778	1.093 (3)
slou	1.138 (4)
Blimp-1	1.206 (5)

All TFs

Cofactor	Euclidean distance (rank)
MBD-like	1.229 (1)
H	2.054 (2)
bon	2.575 (3)
tlk	2.835 (4)
MTA1-like	2.884 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
NK7.1	0.986 (1)
peb	0.983 (2)
Blimp-1	0.980 (3)
CG15269	0.979 (4)
slou	0.976 (5)

All TFs.

Cofactor	Pearson correlation (rank)
H	0.986 (1)
Psc	0.977 (2)
MBD-like	0.969 (3)
Su(z)2	0.953 (4)
HP1b	0.898 (5)

All cofactors.

CDS DNA Sequence²

ATGGACAAAAATCTGATGATGCCGAAGCGTTCGCGCATCGATGTCAAGGGCAACTTTGCCAACGGACCGCTGCAAGCACGCCCACTGGTGGCCCTACTCGATGGACGCGACTGCTCCATCGAGATGCCCATCCTAAAGGATGTGGCCACGGTGGCCTTTTGCGATGCACAAAGCACCTCCGAAATACACGAGAAGGTCCTCAACGAGGCAGTGGGAGCTCTGATGTGGCACACCATCATCTTGACAAAGGAGGATCTTGAGAAGTTCAAAGCTTTACGCATTATCGTGCGCATCGGCAGCGGCACAGACAACATTGATGTAAAGGCGGCGGGCGAACTGGGCATCGCCGTGTGCAACGTTCCCGGCTACGGAGTCGAGGAGGTGGCGGACACGACGATGTGCCTCATCCTCAACCTCTACCGGCGGACATACTGGCTAGCGAACATGGTGCGCGAGGGCAAGAAGTTCACCGGACCCGAGCAAGTGCGGGAGGCTGCGCATGGCTGTGCACGCATCCGCGGCGACACCTTGGGTCTGGTGGGACTGGGCCGCATTGGTAGCGCCGTGGCCCTGCGGGCTAAGGCGTTCGGCTTCAACGTCATCTTCTACGATCCCTACCTGCCCGATGGCATCGACAAGTCGCTGGGCCTAACTCGCGTCTACACGCTGCAGGACCTGCTTTTCCAGTCCGATTGCGTCTCACTGCATTGCACGCTCAACGAGCACAACCATCATTTAATCAATGAATTCACAATTAAACAGATGCGACCTGGTGCATTTCTGGTGAACACCGCACGCGGCGGTCTGGTCGATGACGAGACCCTGGCGTTGGCGCTGAAGCAGGGAAGGATAAGAGCTGCCGCCCTGGACGTTCACGAAAACGAACCTTACAATGTATTTCAAGGCGCACTGAAGGATGCCCCAAATCTGATTTGCACACCGCACGCCGCCTTCTTCAGCGACGCGTCCGCAACGGAGCTGCGCGAAATGGCAGCCACCGAGATCCGGCGGGCGATCGTCGGCAATATTCCAGACGTGCTGAGGAATTGCGTCAACAAGGAGTACTTCATGCGCACGCCGCCTGCCGCTGCCGCCGGGGGCGTGGCGGCGGCTGTTTATCCCGAAGGTAAACTACAAATGATATCAAATCAAGAAAAG

CDS AA Sequence²

MDKNLMMPKRSRIDVKGNFANGPLQARPLVALLDGRDCSIEMPILKDVATVAFCDAQSTSEIHEKVLNEAVGALMWHTIILTKEDLEKFKALRIIVRIGSGTDNIDVKAAGELGIAVCNVPGYGVEEVADTTMCLILNLYRRTYWLANMVREGKKFTGPEQVREAAHGCARIRGDTLGLVGLGRIGSAVALRAKAFGFNVIFYDPYLPDGIDKSLGLTRVYTLQDLLFQSDCVSLHCTLNEHNHHLINEFTIKQMRPGAFLVNTARGGLVDDETLALALKQGRIRAAALDVHENEPYNVFQGALKDAPNLICTPHAAFFSDASATELREMAATEIRRAIVGNIPDVLRNCVNKEYFMRTPPAAAAGGVAAAVYPEGKLQMISNQEK

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.