Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
dve (FBgn0020307)	TF	(-1.25/-4.05/-0.40)	7	◼	◼	◼	◼	◻

Factor activity

Celltype:
S2
Kc167
BG3
OSC

Additional information

dve [FlyBase] | dve [FlyMine] | dve [BDGP]

H. sapiens orthologues¹

None.

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
Oaz	0.585 (1)
bap	0.591 (2)
CG15269	0.600 (3)
CG16778	0.708 (4)
hkb	0.748 (5)

All TFs

Cofactor	Euclidean distance (rank)
MBD-like	1.100 (1)
CtBP	1.320 (2)
bon	2.282 (3)
XNP	2.320 (4)
Mi-2	2.385 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
tll	0.991 (1)
Kr-h1	0.991 (2)
CG2199	0.990 (3)
bap	0.989 (4)
CG4360	0.988 (5)

All TFs.

Cofactor	Pearson correlation (rank)
H	0.980 (1)
MBD-like	0.978 (2)
Su(z)2	0.971 (3)
CtBP	0.966 (4)
Psc	0.962 (5)

All cofactors.

CDS DNA Sequence²

ATGGACTTCCAGAGCGCCATGGAAACCTTTGCCGAAGCCTGGGTGGCAGCCAATGCCGGTCAGCAGAGTCAGGCCTTGGCCTTAACCAGAGCTGTCAACGCGGCCGCCGTTGTGGCCTCGGCCAATGCCAAATCCCCCAATGCCTCCTCCTCCGCCTCGGCCAGCCTGGCGGATCTGGCCGTCAAGAAGGAGCACTCCATCTCGCCGCCCCACAGTGTGGTGAGCGTGGGTGTGGGCGTGGCTGGCGAGGATCAGCATCGCAGATCCTCGTTGCAGGGTGTGCAGGAGAAGCTCACCCAGCTGCAGATGCAGCAGCAGCATCACCAGCAGCAGCAGCAACAGCAGCAGCAGCAACAGCAACAGCACCAGCAGCAGCAGCAACATCATCATCATCAGCAGCAAGCACAGCAGGCAGGCGCTGGAGTGGGTAGTGGCGAGCTGGCTGGACGCAGATCCTCCGAGGGCACACCACCCACCGCCCATCCCCCAACGAACTCCGAGGGACAGGCGCTCTCCTCCTCCACAGCCTCATCTAGTCAGAATGCCACCCCCAAGAGCGATCGGGAAAGGGAGCGTGAGCGGGAGAGGGATCGGGAGGAGCGCGTGGAGCGGGGCAGCATATCCTGCCTCCCACCAGCCGCCCTTGGAATGGCCGTGGGCGTCCAGCAGGCCCAGCATCAGGAGAAGCTGCTCAGCCATCCGGCCTTGGATTCGCGACGGGAGTTCGACGTCAGCAAAGTGAATCCCAAATCACTTCCACTTCACTGTGTGGTGGAGTCGGTGCACTCACTGCACGCCTCCCTGACCATCGACACTCGCCAGCCCTGGAAGAGGCGGCCCAATATCGAGACCGACAGCTACGTGATCATCGCCGCGGCCACGCCCTGGAGCGAGATTGTTCAGACGGCGCTCCAGAGGCTCGGCTACTCCCAGGAGGTGGCCAACACAGCCAGAGGCTCATTAATAATCAAACATTGGAAACCCATACCCCTGGAGCAGATATCGGACAATCCAGCGGTGCCCGTCAGCGATATTGTGGGTGAATTGACTTCCGTGATCACGCTGAGGATCGTGATTCTGCGCCCCAAGACTTCGCCGTTCGGGGAGATCAAGGACAAGCTGCTCAAGCTGCTGGTGCTTCAGTCGCATGCGGTGCTCCGTTCCACAGGATGTCCGCTGGATGAGGTGACGCTATCCCAGATCTGCCGGAGTTCCCACCAGAACACCTACGCCCTGCCAGGAGGAGAGATCTCCGACGAACTGCGCCGCAAGTTCGACCAGTGGTGGTCCAATCAGCTCTCTCCCCAAGCGACCGCCATGACGCCCAAGATGCTGCCGTTCATGACGGGTCCTTCAGCGGTTCCGGTTCCAGTGGCAGTGCCCGGCGAGATGGACTTTCCGGTAGGCACGGCCATGGCGGCGGCGGCCGCTGCGGCGGCTCATGCTGCCGCTGCCGGTGGAGCAGCGGGCGGCAATCCCCTGGGATCGATGGGTAGTCGCGAGAGTCTGTTGCTGGCTAACGAGGCTGCTCACCATGCGGGCGCTGGACAGGCTCCGGGACCAGGACATCACGGCAGCATGCTGGTGCATCCGATGCACGCGTCCATGCACCACCATCACCATCATGGCGGCGGCGGTGGACACGGTCCTCCGTATCCCAATCAGAAGACTCGCATGCGCACCAGCTTCGATCCGGAGATGGAGCTGCCCAAGCTGCAGAAGTGGTTCGCCGACAATCCGCATCCTTCGCGACAGCAGATCCAGACGTATGTGGTGCAGCTGAATGCCCTGGAGTCTCGCCGGGGAAGGAAGCCCCTGGATGTGAACAACGTGGTCTACTGGTTCAAGAACGCTCGGGCGGCTCAAAAACGGGCAGAGATGCGGGGTGGTAGTCTGGGCAGTGCGATCAGTGCCCTGGGTCACGCCGCCATGAACGGCTATCTGAGTCAGCACGCCCCTTTGGGCCAGAATTCCAGCAGCAGTGCTGGTAGCCAGCCCATGAGCATGGGCAACCTGTCCATGTCGCACGACTACCTAAAGAGTCCGCTCAGCCTGAAGTCGGAGGACATTGACACCATGTCGCAGCACTCGGACGACATGGACGAGGAGCAGAGCAGACCGAACACGCCACAACTGCCCCTTTCGCTGACCACCCACGAGCGGCATCGCAGCTCACCGCTGATGGACGAGGACGAGGATGAGGCGGGAGAGCAGCAGCAGCCACAGGAGGCCAAAAGCGATGGAATGAACGGTAGTGTGAAGGATGAGGAGCGGCAGGAGAAGTCGCGCGATGAACTGCAGGACAACGAAAAGGAGAACTCCAACGGGGAAGACCGTCATCTGGATGCAGACGCCCAGATGGAGGCCAGTTCCAACCTCAACAATAACCACAACAACAGCAGCTTGCACATTGAGCAGGAGGTGGGCTCCACACCCAAGCGCTCCACGCCCAAGGAGGAGGACGACGACTTGGATATGGACGAGGATGAGGAGGACAACGAAAACGATGCCAGCCATTTGGACGAGTTTCGCTCGCCCTCGCCGGATCTAGCAGGTGGAGTTGTGCCCCACAAGGACCAGCTGCCCTTTCCTATGGTTCCCAACTCCATGTTCTCGCAGTCCTTCATGTACATGAGCCACTACATCCCGGCATTCGGTCAAGCGGCCGCCGGACATCCGCATCACCATGCTGCCGCTGCAGCGGCAGCTGCCGGAATCCAACCCAACGCCCTCATGGGCGGCGGCGGCCTCAACCTGTCGAGCATATCGAACGAGGAGCGCCGGAAGCGAAACCGCACCTTCATCGACCCGGTGACCGAGGTGCCCAAGCTGGAGCAGTGGTTCGCCATGAACACACATCCCTCGCACAACCTCATCCTCAAGTACACCGAGGACTTGAACACCATGCCATATAGGCAAAAGTTCCCGCGCTTGGAGAGCAAAAACGTGCAGTTCTGGTTCAAGAATCGACGGGCCAAGTGCAAGCGCCTCAAGATGTCGCTGTACGACAGCAATCAGTGCGCCCAGCTGGGAGGACTCGGCTCTTTTGTGCCCAAGTACGAGGAGCGGGAC

CDS AA Sequence²

MDFQSAMETFAEAWVAANAGQQSQALALTRAVNAAAVVASANAKSPNASSSASASLADLAVKKEHSISPPHSVVSVGVGVAGEDQHRRSSLQGVQEKLTQLQMQQQHHQQQQQQQQQQQQQHQQQQQHHHHQQQAQQAGAGVGSGELAGRRSSEGTPPTAHPPTNSEGQALSSSTASSSQNATPKSDRERERERERDREERVERGSISCLPPAALGMAVGVQQAQHQEKLLSHPALDSRREFDVSKVNPKSLPLHCVVESVHSLHASLTIDTRQPWKRRPNIETDSYVIIAAATPWSEIVQTALQRLGYSQEVANTARGSLIIKHWKPIPLEQISDNPAVPVSDIVGELTSVITLRIVILRPKTSPFGEIKDKLLKLLVLQSHAVLRSTGCPLDEVTLSQICRSSHQNTYALPGGEISDELRRKFDQWWSNQLSPQATAMTPKMLPFMTGPSAVPVPVAVPGEMDFPVGTAMAAAAAAAAHAAAAGGAAGGNPLGSMGSRESLLLANEAAHHAGAGQAPGPGHHGSMLVHPMHASMHHHHHHGGGGGHGPPYPNQKTRMRTSFDPEMELPKLQKWFADNPHPSRQQIQTYVVQLNALESRRGRKPLDVNNVVYWFKNARAAQKRAEMRGGSLGSAISALGHAAMNGYLSQHAPLGQNSSSSAGSQPMSMGNLSMSHDYLKSPLSLKSEDIDTMSQHSDDMDEEQSRPNTPQLPLSLTTHERHRSSPLMDEDEDEAGEQQQPQEAKSDGMNGSVKDEERQEKSRDELQDNEKENSNGEDRHLDADAQMEASSNLNNNHNNSSLHIEQEVGSTPKRSTPKEEDDDLDMDEDEEDNENDASHLDEFRSPSPDLAGGVVPHKDQLPFPMVPNSMFSQSFMYMSHYIPAFGQAAAGHPHHHAAAAAAAAGIQPNALMGGGGLNLSSISNEERRKRNRTFIDPVTEVPKLEQWFAMNTHPSHNLILKYTEDLNTMPYRQKFPRLESKNVQFWFKNRRAKCKRLKMSLYDSNQCAQLGGLGSFVPKYEERD

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.