Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
Rbsn-5 (FBgn0261064)	TF	(-0.24/-1.88/0.57)	4	◼	◻	◻	◻	◻

Factor activity

Celltype:
S2

Additional information

Rbsn-5 [FlyBase] | Rbsn-5 [FlyMine] | Rbsn-5 [BDGP]

H. sapiens orthologues¹

ZFYVE20 (HGNC:20759, ENSG00000131381)

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
CrebB-17A	0.842 (1)
Hr96	0.913 (2)
CG15435	0.937 (3)
TFAM	1.011 (4)
CG11317	1.043 (5)

All TFs

Cofactor	Euclidean distance (rank)
Chrac-16	1.649 (1)
esc	1.664 (2)
CG43342	1.859 (3)
Trf	1.944 (4)
CG17446	1.955 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
CG11723	0.946 (1)
CrebB-17A	0.938 (2)
Optix	0.933 (3)
CG7691	0.932 (4)
CG8359	0.930 (5)

All TFs.

Cofactor	Pearson correlation (rank)
Chrac-16	0.924 (1)
CG43342	0.885 (2)
Bin1	0.882 (3)
polybromo	0.882 (4)
Su(var)205	0.873 (5)

All cofactors.

CDS DNA Sequence²

ATGTCTGGAAATCCTTTCGACAGCGACGAAGATCAAAGCTCGGCCAGTGGAGAGATACTAGAGGGCTTCCTATGTCCCATTTGCCGTGCGGATCTCAAGTCCATCGATGTGCTCACGGATCATTTTGCCCGCCAGCATGCGGAAGAGGAGGATGCCCTAAAATCCTTTAAAGATATCTTTACCAAGGCGAAAAAGAAGATCCTAAACCCCTTTGAGGATGAAAAAGGTGCATCTGTATCGTCGCCCGCAGGTTCCTCCTCTTCAGCGGCTGGCAAGAATCCCAATGGCAACGGAGATCGCAATGGACCCAGTAATGCCCGCTCCCGTCTAAATGTATTTAACTATATGGCCAGGCAGCAGCCTGGTGCTGAGTGCTCCCACTTCGAGTACTTTCAGTCCATTCGCAATCCTCGCCTGGAGCGATATGCCAGCGAAACAAACAAACTAATCATTCGTTTGCACCGCCTGCTTAAGGATCTGCCAGCGGATTCAGTGCAGCGGCGTCAGCATGAACAGCAAACAGTTGCCTGGCTGGATGGTAGTTCCGTCAAGTTGTGTCCCAGTTGTGCCAAGAGTTTCCACATCGCCCGAAGACAACACCACTGCCGTTTGTGCGGAGGCATAATGTGCAATGATTGCTCCAAGTTCCTGCCCCTGGAAGATGCCATGCAACTAGCCAGTCTTTCCACCACAAGAAGCGAGCCCCTTCAGCAGCTGCATCAGCATGAGAACGCCATCCGGCTGTGCGAACACTGCCTTTGGCTGCTGGACACCCGAAAGGATATGCACGAAAGTCGCACTTGTCGCCCACTCCTCGTCCAGGTCTACGAACAAATTCGTCAACTACAAAAAGAAGTTACCCCGGATCTGGACATGTATCTAAAGATCATCAATAGCTTGAACGAAGGGGACACAATCTTCACGTTGGCGGATGCAGGTGCTTTGCGCGGCAAGATTGGACAAGTGGCAGAGGCCATGGACATGAGGAGCAAGCGCATTCTAGCCATATTTTGTGAACCAGGCAGCCGGGAGGAGGCATTAAAGAAGGCCATTCGGTTGGGCTGCATCCAAGCCATCAAGGAGCGAATGTTATCGCTGCCCCCACTGCCAGAGGAATCGCACATACGCCAGATGCAGGAGCGTAGACGCATGGAAACGGAGCAGCGTATCCTCACCGAACAGCGCATGGCCATGGAAGCCTACGAACGAAATAACATGGCAGCTAACCAATCCAACGTTGGAGTTCCTGGTCCGGAAAGCGGATCCTTTGCCCAAGGGTCTGATCTTCAATCTCTGAACAACTGGTCAGCACCGCAGGCGGCTAGCAAGTCCAGCCTGGACGATCCGCTGATCGAGCAGATAAACATCATTAAGGGCTACATCAAACAGGCTCGCCAGGACATGAACTTTGAGGTGGTGGAGACGCTGGAGCTAAATCTTCGCGAGCTACAGCGCGAAGTGTACGAGCGACAGCGCCAGTCCCAGGGAAGCACCGCCGCCTCACCCACAGAGGCC

CDS AA Sequence²

MSGNPFDSDEDQSSASGEILEGFLCPICRADLKSIDVLTDHFARQHAEEEDALKSFKDIFTKAKKKILNPFEDEKGASVSSPAGSSSSAAGKNPNGNGDRNGPSNARSRLNVFNYMARQQPGAECSHFEYFQSIRNPRLERYASETNKLIIRLHRLLKDLPADSVQRRQHEQQTVAWLDGSSVKLCPSCAKSFHIARRQHHCRLCGGIMCNDCSKFLPLEDAMQLASLSTTRSEPLQQLHQHENAIRLCEHCLWLLDTRKDMHESRTCRPLLVQVYEQIRQLQKEVTPDLDMYLKIINSLNEGDTIFTLADAGALRGKIGQVAEAMDMRSKRILAIFCEPGSREEALKKAIRLGCIQAIKERMLSLPPLPEESHIRQMQERRRMETEQRILTEQRMAMEAYERNNMAANQSNVGVPGPESGSFAQGSDLQSLNNWSAPQAASKSSLDDPLIEQINIIKGYIKQARQDMNFEVVETLELNLRELQREVYERQRQSQGSTAASPTEA

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.