Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
dre4 (FBgn0002183) cofactor
 
(-0.68/-3.69/0.15)

Factor activity

Additional information

dre4 [FlyBase] | dre4 [FlyMine] | dre4 [BDGP]

H. sapiens orthologues1

SUPT16H (HGNC:11465, ENSG00000092201)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGTCGAGCTTTGTGCTGGACAAGGAGGCGTTCGTGCGCCGCGTGAAACGCCTCTACACGGAATGGAGGGCTCCCAGCATCGGACACGATGACGCGCTCAGGAATCTGGACTGCATCATGAGCATCGTGGGCGTCGAAGAGGATGTCATGTACTCCAAGTCCATGGCCCTGCAGCTCTGGCTGCTGGGCTACGAGCTGACGGACACCATCTCAGTGTTTTGCTCGGATGCCGTGTATTTTCTCACTAGCAAAAAGAAAATAGAATTCCTGAAGCAGACGCAGAACATCACCGAAGAAGGTTTTCCGGAAATCAATCTGCTTGTTAGGGATCGGACGGACAAGGACCAGGGCAACTTCGAGAAGCTCATCAAAGCCCTGCAAAACTCGAAGAAGGGCAAGCGTTTGGGCGTCTTCGCCAAGGACGCCTATCCCGGGGAGTTCAGCGAAGCATGGAAGAAATCCCTGACGGCGTCCAAGTTCGAGCATGTGGACATTAGCACTATTATCGCCTACCTCATGTGTCCCAAGGATGAGTCGGAGATCAACAACATACGCAAGGCATCGCTAGTGTCAATGGACATTTTCAACAAGTATTTGAAAGATGAGATCATGGACATTATTGATTCGGATAGGAAAGTCAAACACAACAAGCTCTCAGATGGCTGCGAGGCTGCCATTGGCGAGAAGAAGTACACCAGTGGTCTGGATCCCAGACTCCTCGATATGGCCTACCCACCCATCATCCAATCGGGAGGAGCCTACAGCCTGAAGTTCTCCGCGGTGGCGGACAAAAATCCCTTGCACTTCGGTGTGATTGTGTGCTCCTTGGGCGCCCGCTACAAGTCGTATTGCTCAAATATATCGCGCACCTTTCTGGTGAATCCCACCGAGGCCATGCAGGAGAACTACACATTTCTGGTAAGTGTGCAGGAGGAGATTCTCAAGCTGCTGGTTCCGGGCACAAAGCTGTGCGACGTCTACGAAAAGACCCTGGACTTCGTGAAGAAGGAGAAGCCGAGTATGGTGGACAATCTGCCCAAAAGCTTTGGTTTCGCCATGGGCCTAGAGTTCCGGGAGAACTCCATTGTCATCGGACCCAAATGCCAGGCGCTACTCAAGAAGAATATGGTCTTTAATTTGCACGTGGGCATCTCGAATCTGACCAATCCCGAAGCCACCGACAAAGAGGGCAAGAACTACGCCCTCTTCATCGGAGACACTGTGCTAGTAGGCGAACAATCCCCAGCCAGTGTGATGACTCCGTCCAAGAAGAAGATCAAGAACGTCGGCATCTTTATCAAGGACGACAGCGACGAGGAAGATGTGGACGACAAGAAGACCGCTAAAGAAGATCAGGGCACCGAGATCCTGGGCCGCAGCAAGCGCAACGCGGTGCTGGAGTCAAAGCTGCGAAACGAGATCAACACGGAGGAGAAGCGCAAGGAGCACCAGCGCGAGCTGGCTCAGCAGCTGAACGAGCGCGCCAAGGATCGGCTGGCCAGGCAGGGAAACTCGAAGGAGGTCGAGAAAGTGCGCAAGAACACCGTCTCCTACAAGTCCATCAGCCAAATGCCGCGCGAGCCGGAAGTCAAGGAGCTCAAGCTTTACGTGGATAAGAAGTACGAGACCGTCATCATGCCAGTGTTCGGCATCCAGGTGCCGTTCCATATATCCACCATCAAGAACATCTCGCAGTCGGTGGAGGGCGAGTACACGTACTTGCGTATCAACTTCTTTCATCCCGGCGCCACAATGGGTCGCAACGAAGGCGGACTCTATCCTCAGCCAGAGGCCACATTTGTCAAGGAAGTTACATACCGCAGCTCTAATGTTAAGGAACACGGGGAGGTGGGAGCTCCATCCGCAAATCTAAACAATGCTTTCCGGCTGATCAAGGAGGTGCAGAAGCGCTTCAAGACCCGCGAGGCTGAGGAGCGCGAAAAGGAGGATCTTGTGAAGCAAGACACACTCATTCTGTCCCAGAACAAGGGTAATCCCAAGCTGAAGGACCTATACATTCGGCCCAACATCGTGACCAAGCGCATGACGGGCAGCCTGGAAGCGCACAGCAATGGATTCCGCTACATCTCCGTGCGCGGCGACAAGGTGGACATCTTGTACAACAACATCAAAAGCGCGTTTTTCCAGCCCTGCGATGGCGAGATGATCATTCTTCTGCATTTCCACCTGAAGTACGCCATTATGTTTGGCAAAAAGAAGCACGTGGATGTACAGTTCTACACGGAAGTGGGAGAGATCACCACGGATCTGGGCAAGCACCAGCACATGCACGACCGCGACGACTTGGCTGCTGAGCAGGCAGAACGTGAGCTGCGGCACAAGCTCAAGACTGCCTTCAAGAGCTTCTGCGAGAAGGTGGAAACCATGACCAAGTCGGTAGTGGAGTTCGACACGCCGTTCCGTGAGTTGGGATTCCCTGGAGCACCCTTCCGCAGCACGGTGACGCTGCAACCCACCTCGGGCTCCCTGGTCAATCTGACGGAATGGCCACCATTTGTCATCACGCTGGACGATGTGGAGTTGGTGCACTTCGAGCGCGTTCAGTTCCACTTGCGCAACTTCGATATGATATTTGTGTTCAAGGAGTACAATAAGAAGGTTGCCATGGTGAACGCCATTCCTATGAACATGCTGGATCACGTGAAGGAGTGGCTCAACTCCTGCGACATCCGCTATTCGGAGGGTGTTCAATCCCTGAACTGGCAAAAGATCATGAAGACCATCACCGACGATCCTGAGGGATTCTTTGAACAAGGCGGCTGGACATTCTTGGACCCGGAATCGGGCAGCGAAGGCGAAAACGAAACCGCCGAATCCGAAGAGGACGAGGCCTACAATCCCACCGACGCCGAATCGGATGAGGAGTCGGACGAAGATTCCGAGTACTCAGAGGCATCAGAAGACAGCGAGGAAAGCGATGAGGACCTTGGCTCTGATGAGGAATCTGGCAAGGATTGGTCCGATCTGGAGCGCGAGGCTGCTGAGGAAGACCGCAACCACGATTATGCCGCAGATGACAAACCACGCAACGGCAAATTCGATTCGAAGAAGCACGGCAAGAGTTCAAAGCACAGTCGCCGCGACCGCGAGGAGGCTCGATCGTCGTCGCACAGTAAAAAGCACAAGTCGAACTCCTCCTCGTCCTCTTCGCATTTAAAGTCCTCCAGCTCCAAACATGGCAGCTCATCTAGCCCGTCGAAGTCGTCGAAGGACAAGTACAACAGCCGGGACAAGCATCATTCCTCCTCATCGTCCGGAAACAAGAGCAGCAGCAAGGACAAGGATCGCAAGCGCTCGCGGGATGACAGTCGCGACAATGGGCACAAGTCGAAGAAGTCGCGACAT

CDS AA Sequence2

MSSFVLDKEAFVRRVKRLYTEWRAPSIGHDDALRNLDCIMSIVGVEEDVMYSKSMALQLWLLGYELTDTISVFCSDAVYFLTSKKKIEFLKQTQNITEEGFPEINLLVRDRTDKDQGNFEKLIKALQNSKKGKRLGVFAKDAYPGEFSEAWKKSLTASKFEHVDISTIIAYLMCPKDESEINNIRKASLVSMDIFNKYLKDEIMDIIDSDRKVKHNKLSDGCEAAIGEKKYTSGLDPRLLDMAYPPIIQSGGAYSLKFSAVADKNPLHFGVIVCSLGARYKSYCSNISRTFLVNPTEAMQENYTFLVSVQEEILKLLVPGTKLCDVYEKTLDFVKKEKPSMVDNLPKSFGFAMGLEFRENSIVIGPKCQALLKKNMVFNLHVGISNLTNPEATDKEGKNYALFIGDTVLVGEQSPASVMTPSKKKIKNVGIFIKDDSDEEDVDDKKTAKEDQGTEILGRSKRNAVLESKLRNEINTEEKRKEHQRELAQQLNERAKDRLARQGNSKEVEKVRKNTVSYKSISQMPREPEVKELKLYVDKKYETVIMPVFGIQVPFHISTIKNISQSVEGEYTYLRINFFHPGATMGRNEGGLYPQPEATFVKEVTYRSSNVKEHGEVGAPSANLNNAFRLIKEVQKRFKTREAEEREKEDLVKQDTLILSQNKGNPKLKDLYIRPNIVTKRMTGSLEAHSNGFRYISVRGDKVDILYNNIKSAFFQPCDGEMIILLHFHLKYAIMFGKKKHVDVQFYTEVGEITTDLGKHQHMHDRDDLAAEQAERELRHKLKTAFKSFCEKVETMTKSVVEFDTPFRELGFPGAPFRSTVTLQPTSGSLVNLTEWPPFVITLDDVELVHFERVQFHLRNFDMIFVFKEYNKKVAMVNAIPMNMLDHVKEWLNSCDIRYSEGVQSLNWQKIMKTITDDPEGFFEQGGWTFLDPESGSEGENETAESEEDEAYNPTDAESDEESDEDSEYSEASEDSEESDEDLGSDEESGKDWSDLEREAAEEDRNHDYAADDKPRNGKFDSKKHGKSSKHSRRDREEARSSSHSKKHKSNSSSSSSHLKSSSSKHGSSSSPSKSSKDKYNSRDKHHSSSSSGNKSSSKDKDRKRSRDDSRDNGHKSKKSRH

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.