Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
wor (FBgn0001983)	TF	(-1.70/-4.51/-1.05)	3	◼	◼	◼	◼	◼

Factor activity

Celltype:
S2
Kc167
BG3
OSC
HeLa

Additional information

wor [FlyBase] | wor [FlyMine] | wor [BDGP]

H. sapiens orthologues¹

None.

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
CG17181	0.807 (1)
CG9932	0.896 (2)
peb	0.921 (3)
Kr-h1	0.943 (4)
GATAd	0.993 (5)

All TFs

Cofactor	Euclidean distance (rank)
H	1.423 (1)
Sin3A	2.211 (2)
CtBP	2.291 (3)
Psc	2.350 (4)
MBD-like	2.374 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
EcR	0.985 (1)
CG17181	0.971 (2)
Su(var)3-7	0.966 (3)
Doc3	0.962 (4)
GATAd	0.962 (5)

All TFs.

Cofactor	Pearson correlation (rank)
Psc	0.964 (1)
H	0.964 (2)
Su(z)2	0.957 (3)
CtBP	0.941 (4)
MBD-like	0.934 (5)

All cofactors.

CDS DNA Sequence²

ATGGATAAACTCAAGTACAGCCGCTGCCCGCTCAAGAAGCGTCCGATAATGGTGGAGGAGTCCAGCCCAGAGGATCACCTAAGTCATGATGAAGGACCAGTGGACTTGAGTGTGGCCTCGGCTGCAGTGCCTATGGAGCCCCATTGGATGGCTAAATCCGAACCGGAACCTCAGCCGGTGCCCACGGAATTGAGGCGCCGCTTCGATGCAGCCATGAATCAGACCAAGGAGCAGTTGGCCCGTCGCATTTGGGAGGAAACCCGTGAGATAGCCCGCGCTTTTCCGGATGTCTTCACCCGGGAGGAAATCGCCAAGAGTCTTGCTCGCCTGGGTTACGGCGAGTTCGAGTTGCCACCTGAGGAGGAAGTAATGGAGCCGGAGCCGGAACCAGAACAGCATCTGCCTCTTCGATATACAAGAGATGCTAGCCCAACCATCATCAAGGCTGAACCCTCTGATGAGGAACAATTTCCCCTGCGAAACTACAATAACAACCTACTCAAAAGCATAGCCGAGTATGAGGACTGTATGAAAATGCAGAACATCAAAGAGGAGATACCTCCGATTCCATCACCCCAGTTGTTCTATCCACCCCCGACTCCACTGGCCGAACCGGAGGACCTATCCGTAACCCAGAGGAGAGTGCTGAGCGAAAACATGAATCTGCAGAATGTGGCCAGAGCTTTGCTGAGCATGCAACACATGGCTCCGCAACATGCGCCGCCTCCGATAGACATGGAAGAGGATCAGGAGAATCAGGACATCAACCAGCTGAAGATCAAGAGCAGCAATGATCTGTACTACCAGTGCCAGCAGTGCAACAAGTGCTATGCCACCTATGCAGGATTGGTAAAGCATCAACAAACGCACGCCTACGAAAGCACCGAGTACAAGATCATTAGAAGCCAGCCTGGAGGATCAGGTGCGATAGTCGACCAAACCGAGTTTTGCACGGATCAAGCTTCGGCTTTGATTCAGGCAGCTAATGTAGCCTCAGCACAGAGCATGCAAAAGCCAGTGGGAGTGCCGCGATACCATTGCCAGGATTGCGGAAAGAGCTACTCCACCTACTCGGGACTCTCTAAGCACCAGCAGTTCCATTGTCCGTCGGCCGAGGGCAATCAGGTGAAGAAGGTCTTCAGCTGCAAGAACTGCGACAAGACCTATGTGTCCTTGGGCGCCCTGAAGATGCACATTCGCACGCATACCCTGCCCTGCAAGTGTCCCATCTGCGGCAAGGCGTTTTCGCGACCATGGCTCCTCCAGGGTCACATACGCACCCACACGGGAGAGAAGCCCTTCAGTTGCCAACACTGCAATCGGGCCTTCGCGGATAGGTCAAATCTCCGCGCGCACATGCAAACCCATTCGGATGTGAAGAAGTACTCGTGCCCCACCTGCACCAAGTCCTTCTCGCGTATGTCCCTGCTGGCCAAGCACCTGCAAAGCGGTTGCCAGACTGAGCAGAGTGGAGGTCCCAGTGGGTCAGGAGGGGGCTTTGATCAGCAGCAGCTACAGCAGCACCTCCAGGTCTACGAGGAGGGACACAATCCACACCAACTCTACTACGCCGGCAGTGTGGGCAGCAGTAATGGTGAAGAGGAGGAGGGCGGGGAATACCAAATGCAACCACCGGCCATTTAT

CDS AA Sequence²

MDKLKYSRCPLKKRPIMVEESSPEDHLSHDEGPVDLSVASAAVPMEPHWMAKSEPEPQPVPTELRRRFDAAMNQTKEQLARRIWEETREIARAFPDVFTREEIAKSLARLGYGEFELPPEEEVMEPEPEPEQHLPLRYTRDASPTIIKAEPSDEEQFPLRNYNNNLLKSIAEYEDCMKMQNIKEEIPPIPSPQLFYPPPTPLAEPEDLSVTQRRVLSENMNLQNVARALLSMQHMAPQHAPPPIDMEEDQENQDINQLKIKSSNDLYYQCQQCNKCYATYAGLVKHQQTHAYESTEYKIIRSQPGGSGAIVDQTEFCTDQASALIQAANVASAQSMQKPVGVPRYHCQDCGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKSFSRMSLLAKHLQSGCQTEQSGGPSGSGGGFDQQQLQQHLQVYEEGHNPHQLYYAGSVGSSNGEEEEGGEYQMQPPAIY

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.