Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
fd19B (FBgn0031086)	TF	(-0.80/-3.55/0.48)	11	◼	◻	◻	◻	◻

Factor activity

Celltype:
S2

Additional information

fd19B [FlyBase] | fd19B [FlyMine] | fd19B [BDGP]

H. sapiens orthologues¹

FOXJ3 (HGNC:29178, ENSG00000198815), FOXJ2 (HGNC:24818, ENSG00000065970)

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
pita	0.814 (1)
Sry-beta	0.871 (2)
fd64A	0.882 (3)
HLHm3	0.896 (4)
fd96Cb	0.900 (5)

All TFs

Cofactor	Euclidean distance (rank)
CG14220	1.910 (1)
XNP	2.387 (2)
HP1b	2.409 (3)
Mi-2	2.579 (4)
MED10	2.713 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
Sry-beta	0.978 (1)
Doc3	0.974 (2)
pita	0.974 (3)
Doc2	0.974 (4)
hkb	0.973 (5)

All TFs.

Cofactor	Pearson correlation (rank)
H	0.959 (1)
MBD-like	0.955 (2)
CtBP	0.948 (3)
Su(z)2	0.938 (4)
Psc	0.931 (5)

All cofactors.

CDS DNA Sequence²

ATGGATACGACACCAATCTTCCAGTCCAGCTTCTCCATCCGATCGCTGCTCTCCGTGGACAAAAAGGAGGAGTCCCCCATTTCGAAGCACAACTCAGGAAGCAGCTTCAGCTCATGCTCGAGCTCCAGTTCCAACTCCAGCTCGGATTCGATGGCTGCAAAGAGCAATGCAAAGCCGGCTTTCACCTACAGCGCCCTCATAGTGATGGCCATCTGGAGCAGCTCCGAGAAGCGTTTGACCCTAAGCGGGATCTGCAAGTGGATCGCGGACAACTTCCCGTACTATCGCACCCGCAAGAGCGTCTGGCAGAACTCGATCCGGCACAACCTGAGTCTCAATCCGTTCTTCGTTCGGGTGCCGCGAGCTCTCGATGATCCTGGACGTGGCCACTACTGGGCACTCGATCCGTATGCCGAGGATCTGTCCATTGGCGAGACGACGGGACGCCTGCGCCGCAGCAATTGGCAGCAGAATACGGGGGCGAGACCCAAGGTCACAGGTCATCCCTATCAGCGAATGCCATATTATGGGCACGGGCACGGTAACGGCCCATATATCAAGGCACACAGCGCCTACTTCCCCATAATGGACCATCAACACCATGCCGCCATGGTGCAGCACTACCAGGCCATGATGCACAGATACCAGATGATGCCACATCCTCACCATCACCAGCATCAGCATCAGCATCAGCATCCTCATTCTCATTTCATTCAGCAATCAAAGCCCCTTCATATCCAGGAGCCATATCATCATACCCGCTACCATCTTCACCAAGAG

CDS AA Sequence²

MDTTPIFQSSFSIRSLLSVDKKEESPISKHNSGSSFSSCSSSSSNSSSDSMAAKSNAKPAFTYSALIVMAIWSSSEKRLTLSGICKWIADNFPYYRTRKSVWQNSIRHNLSLNPFFVRVPRALDDPGRGHYWALDPYAEDLSIGETTGRLRRSNWQQNTGARPKVTGHPYQRMPYYGHGHGNGPYIKAHSAYFPIMDHQHHAAMVQHYQAMMHRYQMMPHPHHHQHQHQHQHPHSHFIQQSKPLHIQEPYHHTRYHLHQE

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.