Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
Taf10 (FBgn0028398)	cofactor	(-0.26/-3.12/0.25)	12	◼	◻	◻	◻	◻

Factor activity

Celltype:
S2

Additional information

Taf10 [FlyBase] | Taf10 [FlyMine] | Taf10 [BDGP]

H. sapiens orthologues¹

None.

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
exd	1.764 (1)
RunxB	1.781 (2)
CG17361	1.909 (3)
CG11317	2.011 (4)
Crg-1	2.035 (5)

All TFs

Cofactor	Euclidean distance (rank)
Taf12L	0.867 (1)
TfIIA-S-2	0.877 (2)
MED7	0.918 (3)
Sirt4	0.961 (4)
CG4210	1.065 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
mor	0.944 (1)
RunxB	0.919 (2)
exd	0.914 (3)
Crg-1	0.885 (4)
CG17361	0.870 (5)

All TFs.

Cofactor	Pearson correlation (rank)
CG11160	0.982 (1)
MED7	0.980 (2)
RpA-70	0.978 (3)
Parp	0.977 (4)
CkIIbeta	0.976 (5)

All cofactors.

CDS DNA Sequence²

ATGGCTTCCGATGGCGAGGACATCAGTGTTACACCCGCAGAATCCGTAACATCGGCCACGGACACCGAGGAGGAGGATATAGACTCGCCACTAATGCAGTCCGAACTGCATTCCGACGAGGAGCAACCGGACGTGGAGGAGGTTCCTCTGACGACGGAGGAATCGGAGATGGATGAGCTGATAAAGCAGCTGGAGGACTACTCGCCCACCATACCAGACGCCCTCACCATGCACATCTTGAAAACGGCTGGCTTCTGCACAGTGGACCCCAAGATAGTGCGCCTCGTCTCGGTGTCCGCGCAGAAGTTCATCTCGGATATTGCCAACGACGCACTGCAGCACTGCAAGACGCGCACCACGAACATCCAGCATTCCAGCGGACACAGTTCCAGCAAGGACAAGAAAAACCCCAAGGACAGGAAGTACACGCTGGCCATGGAGGACCTGGTGCCGGCACTCGCGGACCACGGCATCACCATGCGCAAGCCGCAGTATTTCGTT

CDS AA Sequence²

MASDGEDISVTPAESVTSATDTEEEDIDSPLMQSELHSDEEQPDVEEVPLTTEESEMDELIKQLEDYSPTIPDALTMHILKTAGFCTVDPKIVRLVSVSAQKFISDIANDALQHCKTRTTNIQHSSGHSSSKDKKNPKDRKYTLAMEDLVPALADHGITMRKPQYFV

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.