Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
MRG15 (FBgn0027378)	cofactor	(-0.18/-2.50/1.10)	6	◼	◻	◻	◻	◻

Factor activity

Celltype:
S2

Additional information

MRG15 [FlyBase] | MRG15 [FlyMine] | MRG15 [BDGP]

H. sapiens orthologues¹

MORF4L1 (HGNC:16989, ENSG00000185787), MORF4L2 (HGNC:16849, ENSG00000123562)

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
Crg-1	1.900 (1)
E2f2	2.203 (2)
CG17361	2.283 (3)
OdsH	2.296 (4)
CG11317	2.322 (5)

All TFs

Cofactor	Euclidean distance (rank)
p16-ARC	1.487 (1)
Taf12L	1.591 (2)
Sirt4	1.594 (3)
MED9	1.699 (4)
Prosalpha7	1.797 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
Crg-1	0.893 (1)
mor	0.858 (2)
BEAF-32	0.851 (3)
exd	0.844 (4)
E2f2	0.834 (5)

All TFs.

Cofactor	Pearson correlation (rank)
CG7837	0.932 (1)
CG12863	0.927 (2)
nht	0.924 (3)
CG32319	0.923 (4)
p16-ARC	0.921 (5)

All cofactors.

CDS DNA Sequence²

ATGGGAGAAGTAAAACCCGCTAAAGTGGAAAACTATAGCACGGGGACCGATGCAAACACTCTGTTCGTGGATGGGGAACGGGTTCTGTGCTTCCACGGACCGCTCATCTACGAGGCCAAGGTTCTGAAAACAAAACCCGATGCGACGCCGGTTGAGTACTACATCCACTACGCGGGCTGGAGTAAAAACTGGGACGAGTGGGTGCCCGAGAACCGAGTCCTCAAGTACAACGATGACAACGTCAAGCGACGTCAGGAACTGGCTCGCCAGTGCGGCGAGCGCTCCAAGAAGGATAATAAGAAAGGCAGCGCCAAGGCCAAGAAAATGGAACAGATGCGGAACGAATCTCGTGCCTCGACGCCGTCTAAGGATAGCAACACCTCGCAATCGACCGCTAGCAGCACACCAACAACTAGCGCCGGACCGGGAAGCAAATCGGAAGCCGGGAGCACTGGCACCACGACTACTAACAGCACCGCCAACTCTACAACCAGCCGGGCCCACCGAAAGTCCACACAATCGACGCCATCCACAGCAAGACCTGGCACGCCGAGTGATAAAAAGGAAGACCCCGCCGCAGCTGAGACCACTGAGGAAGAGGGGCCGGTGGCGCCGAAAAAGAAAAGAATGAGCGAACAACGGCCTTCTCTTACGGGAAGCGATGTAGCAGAAAAGCCGTTGCCGCCCACTACCACTCCATCCACACCCACCACGGAGCCGGCACCGTGTGTGGAAAGCGAGGAGGCCTACGCAGCTAAGGTGGAGGTCAAGATTAAGATACCCGACGAGTTAAAGCACTATCTGACCGACGACTGGTATGCGGTGGTGCGGGAGCACAAACTGCTGGAGCTGCCCGCCAAGGTTACCGTGCAGCAGATCTCTGAGCAGTATTTGGCGCACAAGAAGTCCGTGAAATCGACCAGTGCCAGCAAGGAGGTTGCCATAAACGATGTACTCGACGGAATTGTAGAGTACTTCAATGTAATGCTGGGCTCCCAGTTGCTGTACAAATTCGAACGCACCCAGTACGCGGATGTGATGCAGAAGCATCCGGACACACCGTTGTCCGAGCTTTACGGATCTTTTCACCTGCTGCGTCTGTTTGTCCGCCTTGGCTCAATGCTCAGCTACTCTGCGTTGGATCAGCAGTCCATGCAGAACCTACTCACGCACGTGCAGGATTTCCTTAAATTCCTCGTAAAGAACAGCTCAATATTTTTCAGCATGAGCAACTTTATCAACGTTGATCCCGAGTACGTGCGAAATGCACAG

CDS AA Sequence²

MGEVKPAKVENYSTGTDANTLFVDGERVLCFHGPLIYEAKVLKTKPDATPVEYYIHYAGWSKNWDEWVPENRVLKYNDDNVKRRQELARQCGERSKKDNKKGSAKAKKMEQMRNESRASTPSKDSNTSQSTASSTPTTSAGPGSKSEAGSTGTTTTNSTANSTTSRAHRKSTQSTPSTARPGTPSDKKEDPAAAETTEEEGPVAPKKKRMSEQRPSLTGSDVAEKPLPPTTTPSTPTTEPAPCVESEEAYAAKVEVKIKIPDELKHYLTDDWYAVVREHKLLELPAKVTVQQISEQYLAHKKSVKSTSASKEVAINDVLDGIVEYFNVMLGSQLLYKFERTQYADVMQKHPDTPLSELYGSFHLLRLFVRLGSMLSYSALDQQSMQNLLTHVQDFLKFLVKNSSIFFSMSNFINVDPEYVRNAQ

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.