Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
brm (FBgn0000212) cofactor
 
(0.05/-1.45/1.30)

Factor activity

Additional information

brm [FlyBase] | brm [FlyMine] | brm [BDGP]

H. sapiens orthologues1

SMARCA4 (HGNC:11100, ENSG00000127616), SMARCA2 (HGNC:11098, ENSG00000080503)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGGCCTCGCCCTCTCCGGCGAACAGTCCCATGCCACCGCCACAGGCGCCCAGTCCGATGGCCCCGCCCTCGCAGAGTCCCGCCCCCTCGCCGCACAGCCCGTATCCGCACCAGCAGCCGGGTCCACTGCAAGGACCTCCGCCACCCGGACATCCCGGTGCCTACGGACATCCCATGCAGCACGGACCACCCGGCCAGGGTCCACCTGGGCATCATATGCCACCGCACCACCAGGGGATGATTTTCTCAAAAGGTCCGCACATGGGAATGCAGATGCCGCCGACGGGACCGAACATGTCCCCCTACCAAACCCACGGAATGCCACCCAATGCACCCACACAACCCTGCATAGTGTCACCTGGTGGCCCACCTGGAGGCCCGCCACCTCCGGAGCGCTCGAGCCAGGAGAACCTTCACGCGCTTCAACGCGCCATTGATTCAATGGAGGAAAAGGGCTTGCAAGAGGATCCTCGCTACTCGCAGCTGCTGGCAATGCGAGCAACCTCGAAGCATCAGCACCTTAATGGCAATCAGGTTAACTTGTTGCGCACACAGATCACCGCCTATCGGTTGCTGGCGCGGAACAAGCCCATATCCATGCAGATGCAGCAGGCGTTGCAGGCCGCACAGCAACAGCCACCGCCAGGACCTCCAATTGGGCCACCTGGAGCACCAGGCGGACCGCCACCAGGGAGCCAGCATGCAGGACAACCGCCCGTGCCGCCGCAACAACAGCAACAACCGCCACCTTCAGCAGGAACTCCACCCCAGTGCTCCACGCCGCCCGCAAGCAATCCTTATGGACCGCCAGTTCCTGGCCAGAAAATGCAGGTAGCGCCACCACCGCCACACATGCAACAGGGACAGCCATTGCCACCACAACCGCCACAAGTGGGTGGACCCCCGCCTATACAACAGCAGCAACCACCTCAGCAGCAGCAACAACAGTCGCAGCCCCCGCCACCGGAGCCACATCAGCACCAGTTGCCAAACGGAGGCAAACCCCTGAGTATGGGGCCATCTGGCGGGCAACCACTAATACCTTCATCACCCATGCAGCCACAAGTGAGAGGGACACTGCCAGGAATGCCGCCAGGTAGTCAGGTTCCGCAACCAGGAGGAGGTCCTCAGCGACAGGTACCACCTGCGGGCATGCCGATGCCCAAGCCCAATCGCATTACAACGGTGGCCAAACCCGTCGGTCTGGATCCCATAACATTGCTGCAGGAAAGGGAGAATAGGATAGCAGCCAGGATATCATTGCGCATGCAGGAGTTGCAGCGACTGCCGGCCACGATGTCCGAGGATCTGCGTCTGCAAGCGGCTATCGAGTTGAGGGCCCTAAGGGTCTTGAACTTCCAGCGACAGCTGCGTATGGAGTTTGTTCAGTGCACGAGACGAGATACCACTTTGGAAACAGCGTTAAACATTAAGCTCTACAAGAGGACCAAGAGGCAGGGCCTGCGGGAGGCACGTGCCACCGAGAAGCTAGAGAAGCAACAGAAGCTAGAGGCTGAACGAAAGCGTCGCCAAAAGCATCTGGAGTTCTTGGCTGCTGTGCTTCAGCACGGCAAGGATCTAAGGGAGTTCCACAGAAATAATAAGGCCCAGCTTGCAAGGATGAACAAGGCCGTGATGAATCACCACGCCAATGCCGAGCGTGAACAGAAGAAGGAACAAGAGCGCATCGAAAAGGAACGTATGCGACGTCTGATGGCCGAGGATGAGGAGGGTTACCGCAAGCTGATTGATCAAAAGAAGGATAAGAGATTGGCTTTCCTACTGTCGCAGACAGATGAGTATATTAGCAACCTAACTCAGATGGTGAAACAGCACAAGGACGACCAGATGAAGAAAAAGGAGGAGGAGGGCAAGCGGCTGATACAGTTCAAAAAGGAGCTGCTGATGAGCGGAGAGTACATTGGCATTGATGAGGGCAGCATTGTTGCCGATATGCGGGTACATGTGGTGGAACAGTGCACGGGTAAGAAACTCACCGGCGATGATGCACCCATGCTGAAGCACTTGCACCGCTGGCTGAATATGCATCCTGGCTGGGATTGGATCGACGACGAGGAGGACAGCTGTGGGAGCAACGACGATCATAAACCCAAGGTGGAGGAGCAACCAACGGCAACAGAAGATGCCACCGACAAAGCACAGGCGACGGGCAACGATGAGGATGCCAAGGATCTAATTACCAAGGCCAAGGTGGAGGACGATGAGTACAGGACGGAGGAACAGACGTACTACAGCATCGCTCATACCATTCATGAAAAGGTTGTGGAGCAGACCAGCATCATGGTTAATGGTACGCTCAAGGAATACCAGATCAAAGGCTTGGAGTGGTTGGTTTCGCTGTACAATAACAATCTAAATGGTATTTTGGCCGATGAAATGGGTTTGGGTAAAACCATTCAAACCATTTCGCTGGTAACCTACCTTATGGATCGAAAGAAGGTTATGGGTCCTTACTTGATTATTGTACCACTCTCCACCCTGCCCAATTGGGTGCTGGAATTCGAGAAGTGGGCGCCAGCCGTGGGTGTAGTCAGCTACAAGGGCAGTCCGCAGGGAAGGCGATTGCTGCAAAATCAAATGAGAGCAACCAAGTTCAATGTGCTGTTAACCACATATGAGTACGTGATTAAGGACAAGGCGGTGCTGGCCAAGATCCAGTGGAAATACATGATTATCGACGAGGGTCACCGCATGAAGAACCATCACTGCAAACTCACCCAGGTGCTGAACACCCACTACATTGCCCCCTATCGGTTACTTCTCACGGGTACACCTCTGCAAAACAAGCTTCCCGAGTTGTGGGCGCTACTTAATTTCCTGCTGCCCTCGATCTTTAAGTCCTGCTCCACATTTGAACAGTGGTTCAATGCGCCATTTGCCACCACTGGCGAGAAGGTCGAGCTAAACGAGGAGGAGACCATCCTTATCATTCGTCGTCTGCACAAGGTTCTTCGTCCCTTCCTGTTGCGTCGCCTCAAAAAGGAGGTAGAGCACCAGCTGCCCGACAAGGTCGAGTACATCATCAAGTGCGACATGTCCGCGCTCCAACGCGTTCTCTACAAGCACATGCAGAGCAAGGGTGTCCTGCTCACCGATGGTTCCGAGAAGGGCAAGCACGGCAAGGGAGGCGCTAAGGCGCTGATGAACACGATCGTACAGCTGCGCAAGCTGTGCAACCATCCGTTTATGTTCCAGCACATAGAAGAGAAGTACTGCGATCACACTGGCGGCCACGGAGTTGTATCCGGACCGGATCTGTATCGTGTCTCTGGCAAATTCGAGCTGCTTGATCGCATCCTGCCCAAGCTGAAGGCGACCAATCATCGCGTGCTGCTCTTCTGTCAGATGACCCAATGCATGACCATCATCGAAGACTACCTGGGATGGCGCCAATTCGGCTACCTTCGACTCGACGGTACCACGAAGGCCGAGGATCGTGGCGAACTACTGCGAAAATTCAACGCCAAAGGCTCGGATGTATTTGTCTTTTTGCTATCTACCCGAGCTGGTGGTTTGGGTCTTAATCTGCAGACCGCCGATACTGTAGTAATCTTCGACTCCGATTGGAATCCCCATCAGGATCTGCAAGCCCAGGATCGTGCCCATCGTATTGGTCAACGTAACGAGGTGCGCGTCCTGCGACTAATGACAGTCAACTCAGTGGAAGAGCGCATCTTGGCAGCAGCCAGGTACAAGCTGAACATGGACGAGAAGGTCATCCAGGCTGGTATGTTCGATCAGAAGTCAACGGGTAGCGAGCGACAGCAGTTCCTACAAACGATTCTGCACCAGGATGACAACGAAGAGGAGGAGGAAAATGAGGTGCCCGATGACGAAATGATCAACATGATGATTGCCCGCAGCGAGGAGGAGATTGAAATATTTAAGCGCATGGATGCTGAGCGCAAGAAGGAGGATGAGGAGATCCATCCGGGTAGGGAACGTCTGATCGATGAGTCCGAGCTACCCGACTGGTTGACAAAGGATGATGACGAAGTAGAGCGTTTCCACTATCAGTACGACGAGGATACCATTCTAGGTCGAGGCTCCCGGCAGCGAAAGGAAGTAGACTACACCGATAGTTTGACTGAAAAGGAGTGGCTGAAAGCCATCGACGATGGCGCTGAGTTCGACGAGGAAGAGGAGGAAGACGATTCGAAGCACAAGCGACGAAAGCGTAAGAATCGGAAGGAAGAGTCCGACGATGATTCGTTGATCCTAAAACGGCGACGACGCCAAAATCTGGACAAGCGGTCCAAGAAGCAGATGCACAAGATTATGAGTGCGGTTATCAAGCACAACCAAGATGGACGAACCCTGTCCGAACCGTTCATGAAGTTGCCTTCGCGGCAGAGGTTGCCCGACTACTACGAGATCATTAAGCGGCCAGTTGATATTAAGAAAATCCTGCAGCGCATTGAGGACTGCAAGTATGCCGATCTCAACGAGCTAGAGAAGGACTTTATGCAGCTATGCCAGAATGCACAGATCTACAACGAAGAGGCGTCCCTGATTTACCTGGACTCGATTGCCCTGCAAAAGGTATTCGTTGGGGCCAGGCAGAGGATAACAGCTGCAGCGGATGCAGCCGCAGTGGCAGCCGGAGATAACACGGGTGAAGCGCACGGCAATGGAGGTTCGGATAATTCGGACAACGACGACGACGATGGCGGCGAAGACGGCTCCGACGACGAGGAGATTGCAACCACTTCAGCGGCGGCTGTCAAAATGAAGCTGAAACTGAACAAATCTCTGGCTAGTGCGCCCGCTACGCCCACGCAATCATCGTCGAATGTGAGCAGCGGAGCGGCTACCACATCCAAGAAGCAGACGCGTCGCAAGCGCTCCCAAAAGAAGTACACTATTTCAGACGATGACGACGATGACATGGAC

CDS AA Sequence2

MASPSPANSPMPPPQAPSPMAPPSQSPAPSPHSPYPHQQPGPLQGPPPPGHPGAYGHPMQHGPPGQGPPGHHMPPHHQGMIFSKGPHMGMQMPPTGPNMSPYQTHGMPPNAPTQPCIVSPGGPPGGPPPPERSSQENLHALQRAIDSMEEKGLQEDPRYSQLLAMRATSKHQHLNGNQVNLLRTQITAYRLLARNKPISMQMQQALQAAQQQPPPGPPIGPPGAPGGPPPGSQHAGQPPVPPQQQQQPPPSAGTPPQCSTPPASNPYGPPVPGQKMQVAPPPPHMQQGQPLPPQPPQVGGPPPIQQQQPPQQQQQQSQPPPPEPHQHQLPNGGKPLSMGPSGGQPLIPSSPMQPQVRGTLPGMPPGSQVPQPGGGPQRQVPPAGMPMPKPNRITTVAKPVGLDPITLLQERENRIAARISLRMQELQRLPATMSEDLRLQAAIELRALRVLNFQRQLRMEFVQCTRRDTTLETALNIKLYKRTKRQGLREARATEKLEKQQKLEAERKRRQKHLEFLAAVLQHGKDLREFHRNNKAQLARMNKAVMNHHANAEREQKKEQERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAFLLSQTDEYISNLTQMVKQHKDDQMKKKEEEGKRLIQFKKELLMSGEYIGIDEGSIVADMRVHVVEQCTGKKLTGDDAPMLKHLHRWLNMHPGWDWIDDEEDSCGSNDDHKPKVEEQPTATEDATDKAQATGNDEDAKDLITKAKVEDDEYRTEEQTYYSIAHTIHEKVVEQTSIMVNGTLKEYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTISLVTYLMDRKKVMGPYLIIVPLSTLPNWVLEFEKWAPAVGVVSYKGSPQGRRLLQNQMRATKFNVLLTTYEYVIKDKAVLAKIQWKYMIIDEGHRMKNHHCKLTQVLNTHYIAPYRLLLTGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPFATTGEKVELNEEETILIIRRLHKVLRPFLLRRLKKEVEHQLPDKVEYIIKCDMSALQRVLYKHMQSKGVLLTDGSEKGKHGKGGAKALMNTIVQLRKLCNHPFMFQHIEEKYCDHTGGHGVVSGPDLYRVSGKFELLDRILPKLKATNHRVLLFCQMTQCMTIIEDYLGWRQFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVIQAGMFDQKSTGSERQQFLQTILHQDDNEEEEENEVPDDEMINMMIARSEEEIEIFKRMDAERKKEDEEIHPGRERLIDESELPDWLTKDDDEVERFHYQYDEDTILGRGSRQRKEVDYTDSLTEKEWLKAIDDGAEFDEEEEEDDSKHKRRKRKNRKEESDDDSLILKRRRRQNLDKRSKKQMHKIMSAVIKHNQDGRTLSEPFMKLPSRQRLPDYYEIIKRPVDIKKILQRIEDCKYADLNELEKDFMQLCQNAQIYNEEASLIYLDSIALQKVFVGARQRITAAADAAAVAAGDNTGEAHGNGGSDNSDNDDDDGGEDGSDDEEIATTSAAAVKMKLKLNKSLASAPATPTQSSSNVSSGAATTSKKQTRRKRSQKKYTISDDDDDDMD

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.