Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
NK7.1 (FBgn0024321)	TF	(-1.45/-4.36/-0.45)	3	◼	◼	◼	◼	◼

Factor activity

Celltype:
S2
Kc167
BG3
OSC
HeLa

Additional information

NK7.1 [FlyBase] | NK7.1 [FlyMine] | NK7.1 [BDGP]

H. sapiens orthologues¹

None.

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
tll	0.691 (1)
CG16778	0.707 (2)
tio	0.719 (3)
CG5204	0.966 (4)
dmrt99B	0.982 (5)

All TFs

Cofactor	Euclidean distance (rank)
CtBP	1.086 (1)
H	1.361 (2)
MBD-like	1.410 (3)
bon	2.338 (4)
tlk	2.558 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
CG16778	0.991 (1)
bap	0.986 (2)
Kr-h1	0.985 (3)
dve	0.985 (4)
CG15269	0.983 (5)

All TFs.

Cofactor	Pearson correlation (rank)
H	0.990 (1)
CtBP	0.986 (2)
Psc	0.982 (3)
Su(z)2	0.971 (4)
MBD-like	0.969 (5)

All cofactors.

CDS DNA Sequence²

ATGATGCCCGAAACTGAACGCGACGCACATTTGGAGGCAGCTGAAATGGCCAGTGGCGCCCTGGCGCATAATTACGGTATTGTTAAGGATCAGCAACAACAGCAGCAGCAGCAGCAACAACTGCATCACCTGCAGCAGCAACATCATCATCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGTCCAACTCCGATCTGTACAAGATGGCCTGCAATGGCTACAACTATAGCAGTCCGCTGACCATACCGCCCACCTCGATGACCACGCACATGGTCAGTCCCATCGGGAACAGCAAGGAGAAGCTGGTGAATATGTTGCGCGTGCGTGACAACAACAACATGGCCAGCACGATCTCCGACAGTCCACCCACAACGTTTCTGCAAAAGCAACTGGAGGCGGTTGTGGCGCCCCGGCCAAGTTCAGTGCATCCCCAGCATCAGCAGCCGCAGCAGCAGACTGTCCAGCTGCAGCAGCAACGGCGTTCGGTCAGCACACCTGCGATTACAACCACACCTGGTCCGCCCACCAATTGGCATGCCCATGTCTATGATCGACTGCCGCCACACCCGACGCCCCACTCCATCGCCGATATCCTGGGCATGTCCTTTGTCAAAAAGGAACGGCCAGAGGTCGCCTTTGATGCCCAAGGACCGGCCAAATCGCCGAATAGCATACTGAAACCGTATCAGGAACAGCAGCCCATTCGAAGCTCCTCCATTTCGATGAGCGATGCCAGCGAGGAGGAGAGTGCCGCTGTTGCTGGGGCAACATCTGCCGCAACAGCAGCAGCAGCAGTGGCAGCAACCATCACAGCAGCAACTGTTGCAACTCCGCTCGATCAGCCGCTAAATCTGTGTGTGGTCAAAAAGTCTCGCGACAGCAACAACTCACCCATGCCGGCCACCAAACAGAGCCAAATCCTCGGAAAGTCTGCTACCAAGAAGGAAAGTTCTGGTAAGCCGGCGGCCAAGAAAAAGAAGCTATCGTCAACTGTGGCTCTACCACCGGATATCAGTCCAACGGGCAGCAGTGACAGTTTGATGCGGGACAAGTTGATGGCCAACAATAGCAGTTCGCCGGGCAGCAATGTGAATGCGCAAATGCAGAGCAATGCGAACAGCACATTGGAGACCACCGAGGATGACTCCGATTCCGGTTCAACGGATGCGCGGCGAAAGAAGAAGGCACGCACCACGTTCACCGGCAGGCAGATCTTCGAGCTGGAGAAGATGTTCGAGAACAAAAAGTATCTCAGCGCCAGCGAGCGCACCGAAATGGCCAAGCTGCTGATGGTCACCGAAACGCAGGTAAAGATCTGGTTCCAAAACCGGCGCACCAAGTGGAAGAAACAGGACAATGTCACAAATAACGAGGCGGCGGAGCACAAATCCTCGAATGCGAAGCCAGGAGCAACAGGCACCGCAACAACAACGCCAAGTGGAGAGCCGACCGACAAGAGATCCAGCAATGCGACTTCACCCACTGTTGGCAATGCCGCCACCATTGCGGAGATCAAGAAATCTCCAAAGTCTCCAAATCGCGGCAGTAACAATAACAACAACAATACGTTAAACAACAATGTTAATAACAGCGAGGGAAAAGTGCCCGCCAAACAGAGTACCACCAAGATTAAAAAGCAGTTAAATGCGCTGCTGGAAAAGACAGTTAAAACGGCTAATCAAGCACATCGAAGTGCAGAATTGGAGAGCAGCGATCAAAAGCCCGCAGTCGAAAAAAGGCCAAATAATAGTAATGAAAATCAATTGCTACACCAGCGTTTGCATCAGCATGCCATACCTTTAACTGTAGAACCAGCCGCTCCACTCGAACAAACCGAGAAATTGGACATAAAACGAGAGGAGTCTCCGCAGCACAGGGAACTGCAGTTAAGTCTCCAAAGGGCGGCAATTCAAAATGGCCAGCTAACGGAAATGGATTTTGAAAGCAAATTGGCCGCGAGTAAAATTTCCATTGCCTTGGCCATGGCCAACAAACAAATGCAGCCGGAAAAGAGGGTCAAAACCGAAAGTTCCTCATCGGAGGGCGAAGGCGATGGAGACGGCGAGGAAGAGGAGGAGGAGGAGGAGGTGTCCTCCAGCGAGCATGGCGATTCCATAGAAGCTCACGATTCCCAGGATCAGGATGTCGCCATGCGGGAGATT

CDS AA Sequence²

MMPETERDAHLEAAEMASGALAHNYGIVKDQQQQQQQQQQLHHLQQQHHHQQQQQQQQQQQSNSDLYKMACNGYNYSSPLTIPPTSMTTHMVSPIGNSKEKLVNMLRVRDNNNMASTISDSPPTTFLQKQLEAVVAPRPSSVHPQHQQPQQQTVQLQQQRRSVSTPAITTTPGPPTNWHAHVYDRLPPHPTPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMSDASEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQILGKSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQSNANSTLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEPTDKRSSNATSPTVGNAATIAEIKKSPKSPNRGSNNNNNNTLNNNVNNSEGKVPAKQSTTKIKKQLNALLEKTVKTANQAHRSAELESSDQKPAVEKRPNNSNENQLLHQRLHQHAIPLTVEPAAPLEQTEKLDIKREESPQHRELQLSLQRAAIQNGQLTEMDFESKLAASKISIALAMANKQMQPEKRVKTESSSSEGEGDGDGEEEEEEEEVSSSEHGDSIEAHDSQDQDVAMREI

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.