Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
DNApol-delta (FBgn0263600) cofactor
 
(-0.79/-3.49/-0.03)

Factor activity

H. sapiens orthologues1

POLD1 (HGNC:9175, ENSG00000062822)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGGATGGCAAGCGCAAGTTTAATGGAACCTCCAATGGACATGCCAAGAAGCCCAGGAATCCTGATGACGATGAGGAAATGGGCTTTGAGGCGGAGCTGGCCGCCTTCGAGAACTCCGAGGACATGGACCAGACTCTGCTAATGGGCGATGGACCCGAGAACCAAACGACCAGTGAGCGTTGGTCCCGTCCGCCGCCCCCAGAACTAGATCCCTCCAAGCACAACTTGGAGTTTCAGCAGCTGGACGTGGAAAACTATTTGGGACAGCCGTTGCCGGGAATGCCAGGTGCCCAAATAGGACCCGTGCCGGTGGTCCGAATGTTTGGTGTCACCATGGAGGGTAACTCTGTGTGCTGCCATGTGCATGGTTTCTGTCCATACTTCTACATAGAGGCGCCCAGTCAATTCGAGGAGCACCATTGCGAGAAACTACAAAAAGCCTTGGATCAAAAGGTTATTGCCGATATTCGCAACAACAAAGATAATGTCCAGGAGGCTGTGCTTATGGTGGAACTGGTGGAGAAGCTGAACATCCATGGATACAATGGAGACAAGAAGCAGAGGTACATCAAAATATCGGTTACGCTGCCCAGATTTGTGGCTGCGGCTTCACGTCTCCTCAAAAAGGAAGTGATCATGTCGGAGATTGACTTCCAGGACTGTCGCGCCTTTGAGAATAACATAGACTTTGACATTCGCTTCATGGTGGACACTGATGTGGTAGGTTGCAATTGGATAGAGCTTCCCATGGGTCACTGGCGAATAAGGAACAGTCACAGCAAGCCGTTGCCTGAATCCCGCTGCCAGATTGAAGTAGACGTGGCCTTCGACAGATTTATATCCCACGAGCCCGAAGGTGAATGGTCCAAGGTGGCTCCCTTCCGGATCCTCTCCTTTGATATTGAATGCGCTGGTCGCAAAGGAATATTTCCGGAAGCCAAAATAGATCCAGTCATCCAGATAGCCAATATGGTGATAAGGCAGGGAGAACGAGAACCTTTCATTAGGAATGTCTTTACCCTAAATGAATGCGCTCCAATCATAGGCAGCCAGGTGTTGTGCCACGACAAGGAGACCCAGATGCTGGACAAGTGGTCTGCCTTTGTCCGGGAAGTTGACCCGGATATTTTGACCGGATATAATATCAACAACTTTGACTTCCCCTATTTGCTTAACCGAGCAGCTCACTTGAAGGTCAGGAACTTTGAGTATTTGGGCAGGATTAAGAACATTCGTTCGGTGATCAAGGAACAGATGTTGCAGTCGAAGCAGATGGGTCGCAGGGAAAACCAGTACGTTAATTTTGAGGGTAGAGTTCCCTTCGATCTCCTCTTTGTCCTGCTGCGCGACTACAAACTACGCTCGTACACTCTCAACGCTGTGAGCTATCACTTTCTGCAGGAGCAAAAGGAGGATGTGCATCATAGCATTATCACAGATCTTCAGAATGGAGACGAGCAGACACGTCGACGTTTGGCCATGTACTGCCTAAAGGATGCCTACTTACCGCTTAGATTGCTGGAAAAGTTAATGGCCATTGTTAACTACATGGAGATGGCCAGGGTGACGGGTGTGCCACTGGAGTCCTTGCTCACCCGCGGACAACAGATAAAGGTTTTAAGTCAATTGCTGCGCAAGGCCAAAACCAAGGGATTCATCATGCCCTCGTACACCTCTCAGGGATCGGATGAACAGTATGAAGGAGCGACTGTGATTGAACCAAAACGTGGCTACTATGCGGACCCCATCTCCACGCTGGATTTCGCCTCCCTGTATCCAAGTATAATGATGGCGCATAATTTGTGCTACACCACCTTGGTTTTGGGTGGAACTCGTGAGAAGCTGCGGCAGCAGGAGAACCTGCAGGACGATCAAGTGGAACGTACGCCTGCAAACAACTACTTTGTGAAGTCTGAGGTGCGTCGTGGTCTGCTCCCTGAGATTCTGGAATCTCTTTTGGCGGCCAGAAAGCGTGCCAAAAATGACCTAAAAGTGGAAACAGATCCGTTTAAAAGAAAGGTCCTGGATGGCAGACAGCTGGCGCTGAAGATTTCGGCTAATTCCGTGTACGGATTTACTGGCGCACAGGTTGGAAAGTTGCCATGCTTAGAGATCTCGGGCAGCGTCACCGCCTACGGTCGTACCATGATCGAGATGACGAAAAACGAAGTGGAATCCCATTACACACAGGCCAATGGCTACGAGAACAATGCAGTGGTCATCTACGGCGACACTGATTCTGTGATGGTTAATTTCGGAGTAAAAACTCTGGAGCGCAGCATGGAGCTGGGACGCGAGGCTGCCGAACTGGTCAGTTCCAAGTTCGTGCATCCTATTAAATTGGAATTCGAGAAAGTTTACTATCCTTACCTGCTGATTAACAAGAAACGCTATGCGGGATTATACTTTACGCGCCCAGATACCTACGATAAAATGGATTGCAAGGGCATAGAAACCGTGAGGAGAGATAACTCTCCGCTGGTGGCCAACCTGATGAACTCCTGCCTGCAGAAACTACTCATCGAAAGGGATCCCGATGGTGCAGTTGCCTATGTGAAACAGGTGATAGCCGATCTCCTCTGCAATCGCATCGACATCTCGCACTTGGTCATAACCAAGGAGTTGGCCAAAACGGATTACGCAGCCAAACAGGCACACGTTGAGCTGGCCGCCAAGATGAAGAAAAGAGATCCCGGTACGGCGCCCAAACTGGGGGATCGAGTTCCCTATGTGATCTGTGCGGCAGCCAAAAACACACCCGCTTACCAGAAGGCCGAGGATCCGCTGTATGTGCTGGAAAACAGCGTGCCCATCGATGCCACTTACTACCTGGAACAGCAGCTGTCTAAGCCGCTGCTAAGGATCTTTGAACCTATTTTGGGCGACAATGCCGAGTCAATTTTGTTAAAAGGAGAACACACGCGCACACGAACTGTGGTAACATCCAAAGTGGGTGGACTTGCTGGATTTATGACCAAGAAAACGTCGTGTTTGGGCTGTAAATCCCTGATGCCCAAGGGCTACGAACAGGCCTGTCTGTGTCCACACTGCGAGCCACGAATGAGTGAGCTGTATCAGAAGGAGGTGGGTGCGAAGAGGGAACTGGAGGAGACCTTCTCTCGCCTATGGACCGAGTGCCAGCGATGCCAGGAATCCTTGCACGAGGAGGTCATCTGCTCCAACAGAGATTGTCCCATCTTCTACATGCGACAGAAGGTTCGCATGGATCTGGACAATCAGGAGAAGCGGGTGTTGCGATTCGGCCTGGCCGAGTGG

CDS AA Sequence2

MDGKRKFNGTSNGHAKKPRNPDDDEEMGFEAELAAFENSEDMDQTLLMGDGPENQTTSERWSRPPPPELDPSKHNLEFQQLDVENYLGQPLPGMPGAQIGPVPVVRMFGVTMEGNSVCCHVHGFCPYFYIEAPSQFEEHHCEKLQKALDQKVIADIRNNKDNVQEAVLMVELVEKLNIHGYNGDKKQRYIKISVTLPRFVAAASRLLKKEVIMSEIDFQDCRAFENNIDFDIRFMVDTDVVGCNWIELPMGHWRIRNSHSKPLPESRCQIEVDVAFDRFISHEPEGEWSKVAPFRILSFDIECAGRKGIFPEAKIDPVIQIANMVIRQGEREPFIRNVFTLNECAPIIGSQVLCHDKETQMLDKWSAFVREVDPDILTGYNINNFDFPYLLNRAAHLKVRNFEYLGRIKNIRSVIKEQMLQSKQMGRRENQYVNFEGRVPFDLLFVLLRDYKLRSYTLNAVSYHFLQEQKEDVHHSIITDLQNGDEQTRRRLAMYCLKDAYLPLRLLEKLMAIVNYMEMARVTGVPLESLLTRGQQIKVLSQLLRKAKTKGFIMPSYTSQGSDEQYEGATVIEPKRGYYADPISTLDFASLYPSIMMAHNLCYTTLVLGGTREKLRQQENLQDDQVERTPANNYFVKSEVRRGLLPEILESLLAARKRAKNDLKVETDPFKRKVLDGRQLALKISANSVYGFTGAQVGKLPCLEISGSVTAYGRTMIEMTKNEVESHYTQANGYENNAVVIYGDTDSVMVNFGVKTLERSMELGREAAELVSSKFVHPIKLEFEKVYYPYLLINKKRYAGLYFTRPDTYDKMDCKGIETVRRDNSPLVANLMNSCLQKLLIERDPDGAVAYVKQVIADLLCNRIDISHLVITKELAKTDYAAKQAHVELAAKMKKRDPGTAPKLGDRVPYVICAAAKNTPAYQKAEDPLYVLENSVPIDATYYLEQQLSKPLLRIFEPILGDNAESILLKGEHTRTRTVVTSKVGGLAGFMTKKTSCLGCKSLMPKGYEQACLCPHCEPRMSELYQKEVGAKRELEETFSRLWTECQRCQESLHEEVICSNRDCPIFYMRQKVRMDLDNQEKRVLRFGLAEW

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.