Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
vnc (FBgn0263251)	cofactor	(-0.40/-3.50/0.34)	12	◼	◻	◻	◻	◻

Factor activity

Celltype:
S2

Additional information

vnc [FlyBase] | vnc [FlyMine] | vnc [BDGP]

H. sapiens orthologues¹

NAA10 (HGNC:18704, ENSG00000102030), NAA11 (HGNC:28125, ENSG00000156269)

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
exd	1.640 (1)
RunxB	1.874 (2)
unc-4	2.196 (3)
CG11906	2.241 (4)
E2f2	2.331 (5)

All TFs

Cofactor	Euclidean distance (rank)
CG32319	0.782 (1)
CG6154	0.970 (2)
pr-set7	1.041 (3)
CG11160	1.048 (4)
Chd3	1.049 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
mor	0.961 (1)
exd	0.929 (2)
Crg-1	0.923 (3)
RunxB	0.913 (4)
CG11317	0.885 (5)

All TFs.

Cofactor	Pearson correlation (rank)
pr-set7	0.986 (1)
CG32319	0.986 (2)
Etl1	0.985 (3)
TfIIA-S-2	0.985 (4)
S6kII	0.983 (5)

All cofactors.

CDS DNA Sequence²

ATGAACATCCGCTGCGCAAAACCGGAAGACCTAATGACCATGCAGCACTGCAATCTGCTGTGTCTACCCGAAAACTACCAGATGAAGTACTACTTTTACCACGGACTAACCTGGCCTCAGCTTAGCTACGTGGCCGTTGACGACAAGGGCGCCATTGTGGGCTATGTCCTGGCCAAGATGGAGGAGCCGGAGCCCAATGAGGAGAGCCGCCATGGGCACATCACCTCGCTAGCGGTCAAGCGTTCCTATCGGCGATTGGGCCTGGCCCAGAAGCTCATGAATCAGGCCTCCCAGGCCATGGTCGAGTGCTTCAATGCCCAGTACGTGTCCCTGCACGTGAGGAAGAGCAATCGGGCTGCCCTGAACCTCTACACCAACGCCCTCAAGTTCAAGATCATCGAGGTGGAGCCCAAGTACTATGCCGATGGCGAGGATGCATATGCCATGCGACGCGACCTCAGCGAGTTTGCCGATGAGGATCAGGCCAAGGCTGCGAAGCAGTCAGGCGAGGAGGAGGAGAAGGCGGTCCACAGATCCGGCGGACATGGCCACTCGCACAACCACAGCGGTCACGATGGCCATTGTTGC

CDS AA Sequence²

MNIRCAKPEDLMTMQHCNLLCLPENYQMKYYFYHGLTWPQLSYVAVDDKGAIVGYVLAKMEEPEPNEESRHGHITSLAVKRSYRRLGLAQKLMNQASQAMVECFNAQYVSLHVRKSNRAALNLYTNALKFKIIEVEPKYYADGEDAYAMRRDLSEFADEDQAKAAKQSGEEEEKAVHRSGGHGHSHNHSGHDGHCC

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.