Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
Pcaf (FBgn0020388) cofactor
 
(-0.54/-3.47/0.39)

Factor activity

Additional information

Pcaf [FlyBase] | Pcaf [FlyMine] | Pcaf [BDGP]

H. sapiens orthologues1

KAT2A (HGNC:4201, ENSG00000108773), KAT2B (HGNC:8638, ENSG00000114166)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGTCTGGTGGTCCATCCATAACGATAAAAAGCCAACCAATCGATGGTAACAACACGGGCAACGCTGCGGCGCAACAGCAGCAGCAGGCAGCGAATGGCGCAGCAACCGCTGGTGCATCTGGAGCCGCTGGCAGCGCCCAGAATCCAGGACACGGAGGAGCTGCGTCCGGCGCTGGCAGTGTGCCGGCAGAGGGAACGCGCCAGAACAGCCTACAGCGCATTCAGCAGCGAAAGCAAAAGGTCTTCAATCTGCCCGTGCCACAGAAACTGGCCAAATTGTCGATGTATTCCGCCTGCCAGTCTGAGGGATGCCGTTGCACCGGCTGGAAGACACCGCAGGAAAATCGCCACCGTGACGTCGAGTCCTCCTACTGTCCGGAGTTCAACGAGGAGTGCCGCAACACCAGCTGTCGCCATTCGCTGAGATCGCACATAGCCCATCTGGACAATATATCCAGTTCCAGCATGAACGAGCTACTGGGCGCCATTATAGACATGGAGAACCTATTCATGTCCATGCAGCGCGTCGAGGACGAGGACACCAAGAAGGTGTACCAGTACCTCTTCCGTTTGCTGCGCCAGTGCGTCCTCACGCGCCAGCAGGCGGTCATCCGGGGTCCTCTCGGCGATCCACCATTCGAGACGCCGTGCATCACCAAGGCTGTGCTCTCGTTGGTCTTCTACAAGTACAATCACCTGAGCACGCCTGAACTCCAAACCATGACCGAGGTGGCCAAGACGTTCTTGAACTTTCTGAACCACTACAACTTTGAATCGCCGTCGACCAGGAGAGGAGATCTCACCCACGAGGATGCCTCTAACTACAAAATCAACTACACCAGGTGGTTGGTGTTCTGCCACGTGCCCGCCTTCTGTAACTCCCTGCGCCAATGTGAAACGTCCCTAGTGTTTGGACGAACGCTCCTGCGCACCGTTTTCCAGTGCATGTCGCAGCAGCTGAAAAAGAAGTGCATCTCCGAGCGGGATCGCTTTCCCGAGGACAAGCGTTCGATCATCACGCTGATGCCGAAGTTTTTGGAAACGCTTCGCGCCGAATTGCTCAAGGATGATTCGCCCATCTGGGATACCAGCTACCGCCCGTCAAATTCCTTTGTCATCCAGCAGAGAAAGCGTAACCAGGAGGTGGCAAATGTACCCATTGGTCCCAGTGCAGCAAGCATTGGTGGAAACAAGAGGACCAGTGTGGGTGAACCGCTCCACAAGCGAATCAAAAAGGAGCCCACCGATCGTCCAAGCAGTGAGAATTTGGATGACCTGCCTGCGGATGTAGTAATGCGCGCCATGAAATCGGTGTCCGAGTCGAAGACCACCAACAAAGCGGAAATTCTCTTTCCGGTTAATGTGTCGCGGGATGAGAACGTCAAGGCGGAGGAGCAGAAGCGAGCCATTGAGTTCCATGTGGTGGGCAATTCGCTGACCAAACCGGTGGACAAGCAGACTGTTTTGTGGCTACTGGGCCTGCAGCTCGTATTTGCCTATCAGCTACCCGAGATGCCGCGCGAGTACATCAGCCAGTTGGTTTTCGACACCAAGCACAAAACACTGGCGCTCATCAAGGAAAACCAACCCATCGGCGGCATCTGTTTCCGCCCGTTTCCGTCGCAAGGCTTCACCGAGATCGTTTTCTGCGCGGTCACCATGTCGGAACAAGTTAAGGGCTATGGCACGCACTTGATGAACCACTTGAAGGACTACAGCATACAGAGGGGTATCAAGCATCTGCTCACATTCGCCGATTGCGATGCCATCGGGTACTTCAAGAAGCAGGGTTTCTCCAAGGACATCAAATTGGCGCGACCAGTTTATGCGGGCTACATCAAGGAGTACGATAGTGCTACTCTCATGCACTGCGAGCTGCATCCAAGCATTGTGAACACGCAGTTCATAGCTGTAATTCGCAGTCAGAGCGAGATTCTGAAGGAGCTGATCGCACAGCGCCACAACGAGGTGCAGAAAGTAAGACCCGGCTTGACTTGCTTCAAGGAGGGCCTGCCCGTGATTCCCGTGGAATCGATTCCTGGTCTGCGGGAGATCGGTTGGAAGCCGCAAAATCGTCCGGCGCGCTCATCGCGACCCCTCGAGGAATCCACCGATCCGGAGAAGCTGGCCACGTCCTTTGCATCCGTGCTGCAATCCGTGCGCCAGCACACCACCGCCTGGCCCTTCCTGCGCCCGGTGACCGCGGCCGAAGTTCCGGACTACTACGATCACATTAAATATCCCATGGACCTGAAGACCATGGGCGAGCGCCTGAAGAAGGGTTACTACCAAACGCGCCGCCTGTTCATGGCGGACATGGCGCGCATTTTCTCCAACTGTCGGTTCTACAATTCGCCCGACACCGAGTATTATCGGTGTGCCAACTCCCTGGAGCGCTACTTCCAGACCAAGATGCGCGAGCTGGGGCTGTGGGACAAA

CDS AA Sequence2

MSGGPSITIKSQPIDGNNTGNAAAQQQQQAANGAATAGASGAAGSAQNPGHGGAASGAGSVPAEGTRQNSLQRIQQRKQKVFNLPVPQKLAKLSMYSACQSEGCRCTGWKTPQENRHRDVESSYCPEFNEECRNTSCRHSLRSHIAHLDNISSSSMNELLGAIIDMENLFMSMQRVEDEDTKKVYQYLFRLLRQCVLTRQQAVIRGPLGDPPFETPCITKAVLSLVFYKYNHLSTPELQTMTEVAKTFLNFLNHYNFESPSTRRGDLTHEDASNYKINYTRWLVFCHVPAFCNSLRQCETSLVFGRTLLRTVFQCMSQQLKKKCISERDRFPEDKRSIITLMPKFLETLRAELLKDDSPIWDTSYRPSNSFVIQQRKRNQEVANVPIGPSAASIGGNKRTSVGEPLHKRIKKEPTDRPSSENLDDLPADVVMRAMKSVSESKTTNKAEILFPVNVSRDENVKAEEQKRAIEFHVVGNSLTKPVDKQTVLWLLGLQLVFAYQLPEMPREYISQLVFDTKHKTLALIKENQPIGGICFRPFPSQGFTEIVFCAVTMSEQVKGYGTHLMNHLKDYSIQRGIKHLLTFADCDAIGYFKKQGFSKDIKLARPVYAGYIKEYDSATLMHCELHPSIVNTQFIAVIRSQSEILKELIAQRHNEVQKVRPGLTCFKEGLPVIPVESIPGLREIGWKPQNRPARSSRPLEESTDPEKLATSFASVLQSVRQHTTAWPFLRPVTAAEVPDYYDHIKYPMDLKTMGERLKKGYYQTRRLFMADMARIFSNCRFYNSPDTEYYRCANSLERYFQTKMRELGLWDK

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.