Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
Snoo (FBgn0085450)	TF	(-1.53/-4.16/-0.76)	3	◼	◼	◼	◼	◼

Factor activity

Celltype:
S2
Kc167
BG3
OSC
HeLa

Additional information

Snoo [FlyBase] | Snoo [FlyMine] | Snoo [BDGP]

H. sapiens orthologues¹

SKOR2 (HGNC:32695, ENSG00000215474), SKOR1 (HGNC:21326, ENSG00000188779)

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
bbx	0.776 (1)
tio	0.796 (2)
CG17181	0.876 (3)
tll	0.969 (4)
CG9932	0.988 (5)

All TFs

Cofactor	Euclidean distance (rank)
CtBP	1.708 (1)
H	1.726 (2)
MBD-like	1.729 (3)
Sin3A	2.389 (4)
polybromo	2.578 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
Kr-h1	0.979 (1)
bbx	0.978 (2)
CG5204	0.977 (3)
CG13296	0.977 (4)
tio	0.977 (5)

All TFs.

Cofactor	Pearson correlation (rank)
H	0.972 (1)
Su(z)2	0.971 (2)
CG14220	0.960 (3)
Psc	0.957 (4)
MBD-like	0.955 (5)

All cofactors.

CDS DNA Sequence²

ATGACCGAATACGTGACGCCAATGATTAGCACCGTCTTGAAGAAATACCAGACGAGTGCCACCAAATCGCTCCAGGGACCAGGACACGCCCTCACCACCGCCGGTGTCCTCGACATAGTCACCAATGGCAGGAGCGAGAGTCCTGGCCTCAATGGCAAGTGCCAAGCATCTCCGCCAGTTGTGGCGCTGATCAAAAAGGAAATACTCAGTTCGCCGGAGCCGCAGGATCTGCATCATCACGAATGCTCGACGAGGGGCACGCCGCCACAGATATATTCGCCTGCCACGCCACCCCGTGAACTATCGCAGCCGATTTTATCGGTGGCAGATGCGGGATGTGGGGAGTTGTACGAGACGAAACTGGAGGGCAAGACCATTGGATGCTTCTCCGTGGGCGGCGAGATGAGACTGTGCCTGCCACAGTTTCTCAACAATGTTCTCAATGACTTTTCGCTGGAGCAGATCAACAGGATCTTCGATGAGCTGGGCATCTATTGCTCGCAGTGTACGCACGATCAGCTGGTGGAGTTCAAGGCCGCCAAGATCCTGCCATCCGATGTCAAGGCCAGTGGCCTGATCACCCGAACCGATGCGGAACGCCTCTGTGCCGCCCTGCTTCATCGCTCCGACCGGAATAGCTATGTGCCGATCGAGAGTTTGGCCAAGGGTGCCCTCAGCTTCCACGTGTATCACAAGTGCTTTGGCAAATGCGAGGGTATCTGCACGCCGGACATGTACTCCTATCAGAAACCGACCTGCATCAAGTGCCTGGAGTGCGACGGCTGGTTCTCGCCGCAGAAATTCGTGGGTCATGTGCATCGCAAGTTCGAGAATCACACCTGCCACTGGGGCTTCGATTCGCGCAACTGGCACGACTATCTTCATGTGGCGCTCGATGTGGAGAATCGGGAGAAATACCAGATCATCCTCGATCAGTTGAAGGAGGTGGAGCTCAAGGAGATGCACAAGGCGCAGCGGGAATTGGAGCATAAGAAAAGAAAGGCGGAAATGCTCATGGATGACGGTATGCTCGGCTCGGGTCCTGTTCTTGGATTGGCGGGACATCCACATGGGCTGGTGGGCGCCTTGGCTCCGCCGCCGCCACCGCCAATGAAGCAGCCACAAATGGACATTCCCAGTGGCAAGAAGCAGCTGCAGCAGCTGAAGGGGGCGACGGTGGCCGCTTCCGCTCTGGAATATCAGTACCAGGTCATGTATGCGCACTGTGTGCAGAAGGAGCGGGAGAGGGAGCGAGAGCACCTGCCCCACTCGCATCCCCTGCCCCGTCAGCATCGAGCCGTTTTGGTGGCCACCACACCCTATCCACATTTGCCGCAATATCCGACACCACCCACGCTGAACTCCTCGTCGGCCTTCCGACCTTGGGGGCCAGATACGACCAAAGCTTTTCTGCACGCCTATGGCGCCACGTTGTCATCACTACCCTATGCCTGCCAGGAACCACCAGAGCTACAGAATCCGGAGCGGGTGGTGCGGAGTACGGACAAGCGATATGCGGAGAGGACTTACCAACCCAATGTGGCCTTGGCACCCAGAAAGAGTATACTCTCCAAGGAGAGGGACAAGGATAGGGAGCGAATGGAACGGGAGGTGATGGAACGTCAGAGGTTGAGGGAGAAGGAGACGGATCACCAGGTGGTGCACATCAAGCAGGAGCGATCGCAGACACCCACACCACCTACAGCATCACCGCCCGATGGGGTGGTGCTGCCACTGGATGTCGTCGAACCGCCACACCCCTCCTCGAGTGGCAGCAACTCACCACTACCCGCCCACCTGCCCGCAGCACCAGCCACCGCACCACCCAATGCAGGTGGTGCACCGCCCACACCAACTAACCTTCGGAACATGCGCAGCCCGGAGGAGTTTTCAGCGGGTGGCAGCAATGAGATTACCTCCTCCACCTCACCCCACCACCAGCAGTCGTCGCACCACCAGGTGGTGCAGCCAACGGCAGGTGCTCCACCACCGTCGCAGCACATTATAGCCACCGTTAATCAGCATGCCAAACTTTTGCCCAGCTCCAGTTCCCTGCCAAACGGTAATGGCAGCTCATCGCTAGCCGCCACAAACAACGAACCGAGTCGGATACGGATCAACAAGAACCTGATGAGTCAACAGCCGGTGGTCGCGGTGAGCGGCATGACCCCACATCACCACCAGCATCACCCCACGCACATGCATCACTTTAGCCATGGGTACTACAAAAGCCAGGCCTCATCACCCACTCAATCCTCCAGTGCTGGCTTGAACCTGAGTACCCACTCATCGAACGTGGTCAGTTCGCCGCATCATGCGACTCAACCCAAGACCCATCACAGCTCGGTAGGATCTGGGAACCATGGCTTGCAAAATGGTAAGCCCCATTTGGGCAGTGAATTCGAGTTATCTACGGATACGGATGATACGGATAGTCTGAATGGGGAGCCCGACTCGAGTGCCATGTTACCACCCTGGGAGCAGGCTGTGGAGTCCCTCAGAGAAACTCGACCCAAGGACCGGGAGAGAGTCCTTCTGATACTGCAGAGACTACTGCAGGAGAACGATCAATATCGCTATAACAACATTCAATTGAGTGAACTGCTCCACAAACAGGATGCCCACATAGCCGATCTTACGGAGCAACTCCAACGCTATCGCAGGCAATTCGAAGAGCAGGTCTGTAAAGTAGATCTTCGGAAGATGCCATTCAAGCACCAAACACGACTGGAGAACGTGGTCGAAGCGGGTCGAGGAGAGGCGGAAGAGGACGAGGAGCTGGAGGAAGATGAAATGGAGGATAGGGCTAATAACAATAATCAACAGGAGCTATCTCCCCTTATAAAGGCTCCAGCCAATGGTCTGCGGCGGAGTGTCACGCCGCCAAATTGTTGTGCGAGTGAAGGGGGGGATTGCGAGAAGCCAGATGAGCCTGAAAGCAAGAGAATAAAGCTGCAGGTTGGGGAGAAAGCTGAGGACAAGCAGGTAGAGAATGAGGAAAGTCCTTCCAATGGCACGGAGTCGCACGATCTGGAAAAACTTGAAAAAAATGACGATAAAACAGACCCAACTAATAATCCCAAAAGTCCCCAGCCCAGTCAAATTTCCAGCGACGATGAAATGGAGGAGGATGATGAAGACGAAGACGAGGAGGATGAGGACGAAGAGGTTCAAGTGGAGGCTCCCCACAGTAGTGCACTAGCCACGCCCCCCACGGCCACAACGCCCCTCTCGCCGGACTCGGCGGCAACTGCCGGACAGTTGTTCGATAGTAGTAATAGCAGCGACGAGTCCTCGATGAAGAAGGCCCAGATGTCCGCCTGCCATGCACTGGAAAAAATGAGTAGCAATGTTGGCAGCGACGAGAACAATCAGAGGCTCGCCGAGGAAAGTCAAGAGGATGAGGCGGAGGAGGATCCAGAAGAGGAGGACTCCGATGACGACGAAATGCCATTGCAGCAGCGACAGCAGCAGCAGCGCCAGCGGGTGGCACCCCAAAATGTGCTCAGTGGACCATCCGTCGCTGGACACCATCCAGCGCCAGCACATCCTCCGATGGCCACCAAGGCTAGCAAGAAGCAGACACCACCAGCACCACCCACTGCAGCCGCAACCACCACTGCATCAGCAACAACGAACTGCGAGTTACAAATCAAAAAGGAAATAGCC

CDS AA Sequence²

MTEYVTPMISTVLKKYQTSATKSLQGPGHALTTAGVLDIVTNGRSESPGLNGKCQASPPVVALIKKEILSSPEPQDLHHHECSTRGTPPQIYSPATPPRELSQPILSVADAGCGELYETKLEGKTIGCFSVGGEMRLCLPQFLNNVLNDFSLEQINRIFDELGIYCSQCTHDQLVEFKAAKILPSDVKASGLITRTDAERLCAALLHRSDRNSYVPIESLAKGALSFHVYHKCFGKCEGICTPDMYSYQKPTCIKCLECDGWFSPQKFVGHVHRKFENHTCHWGFDSRNWHDYLHVALDVENREKYQIILDQLKEVELKEMHKAQRELEHKKRKAEMLMDDGMLGSGPVLGLAGHPHGLVGALAPPPPPPMKQPQMDIPSGKKQLQQLKGATVAASALEYQYQVMYAHCVQKEREREREHLPHSHPLPRQHRAVLVATTPYPHLPQYPTPPTLNSSSAFRPWGPDTTKAFLHAYGATLSSLPYACQEPPELQNPERVVRSTDKRYAERTYQPNVALAPRKSILSKERDKDRERMEREVMERQRLREKETDHQVVHIKQERSQTPTPPTASPPDGVVLPLDVVEPPHPSSSGSNSPLPAHLPAAPATAPPNAGGAPPTPTNLRNMRSPEEFSAGGSNEITSSTSPHHQQSSHHQVVQPTAGAPPPSQHIIATVNQHAKLLPSSSSLPNGNGSSSLAATNNEPSRIRINKNLMSQQPVVAVSGMTPHHHQHHPTHMHHFSHGYYKSQASSPTQSSSAGLNLSTHSSNVVSSPHHATQPKTHHSSVGSGNHGLQNGKPHLGSEFELSTDTDDTDSLNGEPDSSAMLPPWEQAVESLRETRPKDRERVLLILQRLLQENDQYRYNNIQLSELLHKQDAHIADLTEQLQRYRRQFEEQVCKVDLRKMPFKHQTRLENVVEAGRGEAEEDEELEEDEMEDRANNNNQQELSPLIKAPANGLRRSVTPPNCCASEGGDCEKPDEPESKRIKLQVGEKAEDKQVENEESPSNGTESHDLEKLEKNDDKTDPTNNPKSPQPSQISSDDEMEEDDEDEDEEDEDEEVQVEAPHSSALATPPTATTPLSPDSAATAGQLFDSSNSSDESSMKKAQMSACHALEKMSSNVGSDENNQRLAEESQEDEAEEDPEEEDSDDDEMPLQQRQQQQRQRVAPQNVLSGPSVAGHHPAPAHPPMATKASKKQTPPAPPTAAATTTASATTNCELQIKKEIA

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.