Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
TfIIA-L (FBgn0011289)	cofactor	(-0.34/-3.18/0.58)	4	◼	◻	◻	◻	◻

Factor activity

Celltype:
S2

Additional information

TfIIA-L [FlyBase] | TfIIA-L [FlyMine] | TfIIA-L [BDGP]

H. sapiens orthologues¹

GTF2A1 (HGNC:4646, ENSG00000165417)

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
RunxB	1.875 (1)
exd	1.983 (2)
zfh1	2.198 (3)
CG6470	2.200 (4)
E(spl)	2.222 (5)

All TFs

Cofactor	Euclidean distance (rank)
TfIIA-S	1.073 (1)
CG6154	1.186 (2)
Rpn3	1.208 (3)
CG32319	1.325 (4)
vnc	1.432 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
Crg-1	0.930 (1)
RunxB	0.927 (2)
mor	0.912 (3)
CG11317	0.911 (4)
CG8119	0.910 (5)

All TFs.

Cofactor	Pearson correlation (rank)
TfIIA-S	0.983 (1)
Rpn3	0.974 (2)
e(y)1	0.974 (3)
CG6154	0.971 (4)
Taf6	0.971 (5)

All cofactors.

CDS DNA Sequence²

ATGGCGCTATGCCAGACATCGGTGCTGAAGGTGTACCATGCCGTGATCGAGGACGTCATCACAAATGTGCGGGACGCGTTCCTGGACGAGGGCGTCGACGAACAGGTGCTGCAGGAGATGAAGCAGGTCTGGCGCAACAAGTTGCTTGCTAGCAAGGCCGTCGAGCTGAGCCCGGACTCCGGCGATGGCTCCCATCCGCCACCCATCGTGGCCAACAATCCAAAGAGCCACAAGGCAGCGAATGCCAAGGCCAAGAAGGCCGCCGCCGCAACCGCGGTCACATCACACCAACATATCGGCGGCAACAGCTCCATGTCCTCGCTGGTGGGGCTTAAGTCGTCCGCTGGAATGGCCGCCGGCAGCGGCATAAGGAACGGGCTGGTGCCCATCAAGCAGGAAGTCAACTCACAGAATCCACCGCCACTGCATCCTACCTCGGCTGCAAGCATGATGCAGAAACAGCAGCAGGCGGCGAGCAGTGGACAGGGTTCCATTCCAATTGTGGCCACGCTGGACCCCAATCGCATTATGCCTGTTAACATCACGCTGCCATCGCCAGCCGGCTCTGCCAGTTCGGAATCTCGAGTGCTCACCATACAAGTGCCTGCCTCCGCGCTGCAGGAGAATCAGTTGACCCAAATTCTGACGGCCCACCTGATTTCATCCATCATGTCCTTGCCCACCACGTTGGCCTCGTCTGTGCTTCAGCAGCACGTAAACGCAGCGCTAAGCAGCGCCAATCACCAGAAAACTCTTGCCGCCGCCAAGCAATTGGACGGTGCCCTGGACTCCTCCGATGAGGATGAAAGCGAGGAGAGCGACGACAACATCGACAACGATGACGACGATGACCTAGACAAGGACGATGACGAGGATGCGGAGCACGAGGATGCTGCCGAGGAGGAGCCGCTCAACAGCGAAGACGATGTCACCGACGAAGACTCTGCCGAAATGTTTGACACAGATAACGTGATTGTTTGTCAGTACGATAAGATCACCAGGTCGCGAAACAAATGGAAATTCTATCTCAAAGATGGCATCATGAACATGCGGGGCAAGGACTACGTGTTCCAGAAATCGAATGGCGACGCCGAGTGG

CDS AA Sequence²

MALCQTSVLKVYHAVIEDVITNVRDAFLDEGVDEQVLQEMKQVWRNKLLASKAVELSPDSGDGSHPPPIVANNPKSHKAANAKAKKAAAATAVTSHQHIGGNSSMSSLVGLKSSAGMAAGSGIRNGLVPIKQEVNSQNPPPLHPTSAASMMQKQQQAASSGQGSIPIVATLDPNRIMPVNITLPSPAGSASSESRVLTIQVPASALQENQLTQILTAHLISSIMSLPTTLASSVLQQHVNAALSSANHQKTLAAAKQLDGALDSSDEDESEESDDNIDNDDDDDLDKDDDEDAEHEDAAEEEPLNSEDDVTDEDSAEMFDTDNVIVCQYDKITRSRNKWKFYLKDGIMNMRGKDYVFQKSNGDAEW

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.