Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
14-3-3zeta (FBgn0004907) cofactor
 
(-0.51/-3.20/0.10)

Factor activity

H. sapiens orthologues1

YWHAZ (HGNC:12855, ENSG00000164924), YWHAB (HGNC:12849, ENSG00000166913)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGTCGACAGTCGATAAGGAAGAGCTGGTCCAGAAGGCTAAACTGGCCGAGCAGTCAGAACGTTACGATGATATGGCCCAGGCCATGAAGTCCGTCACAGAGACTGGCGTTGAGCTCTCAAATGAGGAAAGAAATCTGCTCTCCGTTGCCTACAAAAATGTGGTCGGTGCCCGCAGGTCATCGTGGCGTGTCATCTCCTCCATTGAGCAGAAAACCGAAGCATCCGCTAGAAAACAGCAGCTCGCCCGTGAGTACAGAGAGCGTGTGGAGAAGGAGCTGAGGGAAATCTGCTACGAAGTTTTGGGACTTCTGGACAAATACCTTATTCCAAAAGCCAGCAATCCCGAGAGCAAGGTGTTTTACCTGAAGATGAAGGGTGATTACTACAGGTATTTAGCCGAGGTTGCCACAGGAGATGCACGCAACACCGTCGTTGATGACTCGAAAAATGCCTATCAGGAGGCGTTCGATATTGCAAAAACCAAAATGCAGCCCACGCATCCCATCCGTTTGGGTCTGGCCCTTAACTTCTCAGTCTTCTACTATGAGATTTTGAACTCACCAGACAAAGCTTGCCAATTGGCTAAACAGGCGTTCGATGATGCGATAGCCGAGCTGGACACACTGAACGAGGACTCCTACAAGGACTCGACACTCATCATGCAGCTGTTGAGGGACAACCTGACTCTCTGGACGTCCGACACCCAAGGCGACGAAGCTGAGCCACAGGAGGGCGGCGACAAC

CDS AA Sequence2

MSTVDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRYLAEVATGDARNTVVDDSKNAYQEAFDIAKTKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAEPQEGGDN

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.