Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
Cand1 (FBgn0027568) cofactor
 
(-0.55/-2.98/0.02)

Factor activity

Additional information

Cand1 [FlyBase] | Cand1 [FlyMine] | Cand1 [BDGP]

H. sapiens orthologues1

CAND1 (HGNC:30688, ENSG00000111530), CAND2 (HGNC:30689, ENSG00000144712)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGGCGTCACATCAGTACCACCAAATTGCCAATTTGCTGGAAAAAATGACGTCGACGGACAAGGACTTCCGTTTCATGGCGACAAACGATCTGATGACGGAGCTACAGAAGGATAGCATCATCCTGGACGACGAGTCCGAGAAAAAGGTGGTGCGAATGGTGCTCAAGCTGCTGGAAGACAAGAACGGCGAAGTTCAGAACCTGGCTGTCAAGTGCCTGGGTCCCCTGGTCAACAAGGTGAAGGAGATCCAGGTGGAGACCATCGTGGACTCGCTGTGCGCCAACATGATGTCCAACACGGAGCAGCTGCGCGACATATCGAGTATTGGCCTAAAGACAGTGATTGCCGAGCTGCCGCAGTCCTCAAACTCCCTGGCCCCAAATGTCTGTCAAAGGATCACCGGCAAACTGAGCACAGCAATTGAGAAGGAGGACGTCTCTGTGAAACTGGAGTCGCTGGACATTCTGGCCGATCTGCTCTCTCGCTTCGGGGAGTTCCTCGTTCCCTTCCACAGCACCATTCTGAAAGCTCTGATGCCCCAGTTGGCCTCATCGCGCCAGGCTGTTCGCAAGCGTACCATCGTGGCCCTGTCATTTCTGCTGATCCAGGCCAATAGCAACGCCTACAACGGTGTCATCGATCATCTGCTCGATGGCCTAGAGAACCCACCAAATCCAGCTGCCATTCGAACTTACATTCAGTGCCTGGCTTCGATATGTCGACAGGCTGGCCATCGACTTTGCAATCACATTGATCGCTCCATGCTCCTGCTGAGCCAGTACAGCCAGCGGGATGACGATGAGCTGCGCGAGTTTTGTCTGCAGGCCTGCGAAGCTTTCGTCATGCGCTGCCCAGATGCCATAAACCCGCATATTCCCATGATCCTGGAGCTGTGCCTCAACTATATCACCTACGATCCAAACTACAACTACGAGACGGATGATGGCGACACTGGCAATGCCATGGACACGGAGGATGATGAGTACGTCGATAGTGAGGAGTACAGTGACGACGACGACATGAGCTGGAAGGTTCGTCGCGCTGCAGCCAAGTGTCTGGAGGTCTTGATATCCACACGGCAGGAGCTCGTCGAGGACTTCTATCGCAGCCTGAGTCCGGCTTTGATTGCGCGCTTCAAGGAGCGTGAGGAGAATGTTAAGTCCGACATATTTCACGCCTATGTGGCCCTGCTAAAGAACACACGCCTCACCGACGACGTGGCCAACGACCACGACTCAATGGATCAGGTATCGGGTCCGACCTCGCTGTTAATTGAGCAGCTGCCACTCATTGTGAAAGCCATACAGCCGTTAATGAGGGAAAAATCGATGAAAACGCGTCAAGACTGCTTCCTCTTGCTGCGCGAGCTGTTGATTTCGCTACCAGGTGCCCTGGGACCCTACTTGGACAGCATTGTGCCAGGCATAAGCTATTCGCTGAATGACAAAAGCTCTACCAGCAACATGAAGATCGAATCTCTGGGATTCCTTTACTCGCTGCTCCAAGGACATCCGCCGCATGTCTTTCATCCACATATTCCCCTACTGGTGCCCCTCGTAGTGACTTCGGTCTTCGATCCTTTCTATAAGATTGCCACCGAGGCGCTTTTGGTGCTGCAGCAGTTGGTAAAGGTGATTCGTCCATTAGAACCGAATGCGGCCAAGTCCGACTTTGATGCCCCATCGTTTGTGGGTCAGGTTTACTCGTGCACATTGCAGAAACTGAAAGTGACGGATGTCGACCAGGAGGTAAAGGAGCGAGCCATAGCCTGCATGGGGCAGATTATCGCCAACATGGGCGACATGCTGCAGAATGAGCTGGCGGTTTGCCTGCCAATCTTCATGGAGCGCCTAAAGAACGAAGTAACCCGTTTGAGCAGCGTGAAGGCGTTGACCCTGATCGCAGCTTCGTCCCTGCGCATAGATCTGACACCCATCCTGCACGACGTGTTGCCCGCATTGGGCACATTCCTGCGTAAGAACCACCGCGCCCTCAAGCTGCACTCCCTCGATCTGATCAACAAGATCGTCATCAACTATTCGAGCAACTTCGAGGCGAACCTTCTGCAGACAGCCATAGTTGAGATCCCACCGCTTATATCGGATTCGGATTTGCACGTAGCCCAGTACTCTCTGACGCTTTTGAGCACCGTAGCTCGCAGGCAGCCCCAAGCTCTGGTCGGCATACATGAGCAGTTCTTGCGCTCCGTGCTCATTTTGGTTCGATCTCCTTTGCTGCAGGGATCCGCATTGAATTGCACGTTGGAGCTGTTCCAGGCCTTGGTGCAAACACAGCTGTCTGGCCTGGACTATCATTCGCTCGTTTCGAAGCTAATGGCACCAGTTCTGGGTGGCAACGGTGACGTCAAATCCAGAGCCACTGCCGGCGCTCCCAGTGAGGTGGTGCAGCTGCACAAGCAGGCCTATCACTCATCGGCCAAGTGCATTGCTGCCTTAACACAGCAGTGTCCCCAGGTGGCGACCCCATTGGCCACAAAGCTGATAACGGATCTGCAGAAGCGTAACGATACGGAAATCATATTCTGTTTGCTCACCATCGGTGAGATTGGCAGGCACTTTGATCTGAGCTCCATACAGGTGCTGCCGCAGACAATTATTGAATGCTTTGGGGCCACCTCGGAGGATGTAAAGGCTGCAGCCTCGCACGCTCTCGGCGCTGTGTCCGTGGGCAGCCTGCAGACATACCTGCCTCTGATTCTGCACGAGATTGAGGTGCAGCCGAAGAGACAGTATTTGCTGCTACATTCGCTTAAGGAGGTCATTTCATCGCTATCGGTATCGCCCAGCGGACTCGCCCAGCTCCTACCCTCGGTGCCATCCATTTGGGATCAGCTCTTCAAGCATTGCGAGTGTTCGGAGGAGGGATCACGCAACGTGGTGGCCGAGTGCCTGGGCAAACTGGTGCTGGTCAATCCCGACGAGCTGCTGCCGCAACTGCAGCAGGCATTGCGTTCCGAAAGCGCCACCATGCGCACCGTTGTTGTCTCCTCAGTAAAGTTTACCATCTCCGATCAGCCGCAGCCCATTGATGTTCTGCTCAAGCAGAACATTGGCGAGTTTCTATTTGCCCTGCGAGATCCGGAGCCCCAAGTGAGACGCGTCGCACTAGTAGCCTTCAATTCGGCGGTACACAACAAGCCCAGTTTGGTGCGCGATTTGCTGCCCACCCTTTTGCCTTGGCTCTACTCGGAGACGAAGGTGAAGAGCGAACTGATTAGGGAGGTGGAGATGGGTCCCTTCAAGCACACCGTCGACGACGGTCTCGACATTCGCAAAGCGGCATTTGAATGCATGTACACACTTCTCGAGCAGGGCTTGGATCGTGTGGATGTCATGCAGTTCCTGGACCATGTCCAGGCTGGTCTGTGCGACCACTACGACATCAAGATGCTGACGTACCTGATGACGGCACGTCTGGCCATCTTGTGCCCGGATAAGGTTCTGCTAAGACTCGATCAATTTATACAGCAACTACGTGATACGTGCACCCACAAGGTGAAGGCCAACTCTGTGAAACAGGAGTACGAAAAGCAGGACGAACTCAAGCGTTCTGCCCTTCGTGCAGTCTCGGCCCTTTCGCAAATACCCAAAGCAAACAAAAATCAGCAGTTAGTGGATTTCCTCAAGTCGATCAAAGAAACACCGGAATTAAACAAGATCTTCGAGTACATACAGAAGGATTCCATCACCGGTAGCTCAGATATTATAGTAATGGATCAGAGT

CDS AA Sequence2

MASHQYHQIANLLEKMTSTDKDFRFMATNDLMTELQKDSIILDDESEKKVVRMVLKLLEDKNGEVQNLAVKCLGPLVNKVKEIQVETIVDSLCANMMSNTEQLRDISSIGLKTVIAELPQSSNSLAPNVCQRITGKLSTAIEKEDVSVKLESLDILADLLSRFGEFLVPFHSTILKALMPQLASSRQAVRKRTIVALSFLLIQANSNAYNGVIDHLLDGLENPPNPAAIRTYIQCLASICRQAGHRLCNHIDRSMLLLSQYSQRDDDELREFCLQACEAFVMRCPDAINPHIPMILELCLNYITYDPNYNYETDDGDTGNAMDTEDDEYVDSEEYSDDDDMSWKVRRAAAKCLEVLISTRQELVEDFYRSLSPALIARFKEREENVKSDIFHAYVALLKNTRLTDDVANDHDSMDQVSGPTSLLIEQLPLIVKAIQPLMREKSMKTRQDCFLLLRELLISLPGALGPYLDSIVPGISYSLNDKSSTSNMKIESLGFLYSLLQGHPPHVFHPHIPLLVPLVVTSVFDPFYKIATEALLVLQQLVKVIRPLEPNAAKSDFDAPSFVGQVYSCTLQKLKVTDVDQEVKERAIACMGQIIANMGDMLQNELAVCLPIFMERLKNEVTRLSSVKALTLIAASSLRIDLTPILHDVLPALGTFLRKNHRALKLHSLDLINKIVINYSSNFEANLLQTAIVEIPPLISDSDLHVAQYSLTLLSTVARRQPQALVGIHEQFLRSVLILVRSPLLQGSALNCTLELFQALVQTQLSGLDYHSLVSKLMAPVLGGNGDVKSRATAGAPSEVVQLHKQAYHSSAKCIAALTQQCPQVATPLATKLITDLQKRNDTEIIFCLLTIGEIGRHFDLSSIQVLPQTIIECFGATSEDVKAAASHALGAVSVGSLQTYLPLILHEIEVQPKRQYLLLHSLKEVISSLSVSPSGLAQLLPSVPSIWDQLFKHCECSEEGSRNVVAECLGKLVLVNPDELLPQLQQALRSESATMRTVVVSSVKFTISDQPQPIDVLLKQNIGEFLFALRDPEPQVRRVALVAFNSAVHNKPSLVRDLLPTLLPWLYSETKVKSELIREVEMGPFKHTVDDGLDIRKAAFECMYTLLEQGLDRVDVMQFLDHVQAGLCDHYDIKMLTYLMTARLAILCPDKVLLRLDQFIQQLRDTCTHKVKANSVKQEYEKQDELKRSALRAVSALSQIPKANKNQQLVDFLKSIKETPELNKIFEYIQKDSITGSSDIIVMDQS

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.