Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
Rpd3 (FBgn0015805) cofactor
 
(-1.07/-3.82/-0.31)

Factor activity

Additional information

Rpd3 [FlyBase] | Rpd3 [FlyMine] | Rpd3 [BDGP]

H. sapiens orthologues1

HDAC2 (HGNC:4853, ENSG00000196591), HDAC1 (HGNC:4852, ENSG00000116478)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGCAGTCTCACAGCAAAAAGCGCGTTTGTTACTACTACGACAGCGACATTGGCAACTACTACTATGGCCAGGGTCATCCCATGAAGCCCCATCGCATACGCATGACCCACAACCTGCTGCTCAACTATGGGCTCTATCGAAAAATGGAAATATACCGTCCCCATAAAGCCACTGCCGATGAGATGACCAAGTTCCACTCGGACGAGTACGTCCGGTTCTTGCGATCCATTCGGCCGGACAACATGTCGGAGTACAACAAGCAGATGCAGCGTTTCAATGTCGGCGAAGATTGTCCCGTCTTCGATGGACTATACGAGTTTTGCCAACTCTCCGCCGGAGGATCCGTAGCTGCGGCCGTAAAACTGAATAAGCAAGCCTCGGAGATCTGCATCAATTGGGGCGGTGGGCTGCATCACGCCAAAAAATCGGAAGCCTCGGGCTTCTGCTACGTCAACGACATTGTTCTGGGAATTCTGGAACTGCTTAAATACCATCAGCGTGTTCTCTACATAGATATAGACGTCCATCACGGCGATGGCGTGGAGGAGGCGTTCTATACCACCGATCGTGTGATGACTGTCAGCTTCCACAAGTACGGAGAGTATTTCCCGGGCACTGGCGATCTGCGAGACATTGGCGCCGGCAAGGGAAAGTACTATGCGGTGAATATACCCCTGCGTGATGGCATGGATGATGATGCGTACGAGAGCATATTTGTGCCCATTATCAGCAAGGTGATGGAAACATTCCAGCCGGCAGCCGTGGTGTTGCAGTGTGGCGCCGATTCGCTGACTGGCGATCGGTTAGGCTGCTTCAATCTCACCGTCAAGGGTCACGGCAAGTGCGTGGAGTTCGTGAAGAAATATAACCTGCCATTCCTGATGGTCGGCGGTGGTGGTTATACCATTCGTAATGTATCCCGCTGCTGGACCTATGAGACCTCCGTTGCACTGGCCGTGGAGATAGCCAACGAACTGCCCTACAACGATTACTTCGAGTACTTTGGGCCCGATTTTAAGCTGCACATTAGTCCCAGCAATATGACGAATCAGAATACATCCGAGTACCTGGAGAAGATCAAGAACCGTCTGTTCGAGAACCTGCGCATGCTGCCTCACGCTCCGGGCGTTCAAATCCAAGCGATTCCCGAGGATGCCATCAACGATGAGTCCGACGACGAGGACAAGGTCGACAAGGATGATCGCCTGCCGCAGAGCGACAAGGACAAGCGCATTGTGCCCGAGAACGAGTACTCCGATTCGGAGGATGAGGGCGAAGGCGGTCGCAGGGATAACCGTTCGTACAAGGGTCAGCGGAAGCGGCCGCGTCTCGACAAGGACACCAACAGCAACAAGGCATCCTCAGAGACGTCCAGCGAGATCAAGGACGAAAAGGAAAAGGGCGACGGAGCTGATGGCGAGGAATCGACGGCGTCTAATACCAATAGCAACAACAACAGTAACAACAAGAGCGATAATGATGCCGGAGCGACAGCTAATGCCGGATCCGGTTCGGGATCAGGTTCCGGTGCCGGGGCCAAGGGCGCCAAGGAGAACAACATT

CDS AA Sequence2

MQSHSKKRVCYYYDSDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDEYVRFLRSIRPDNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVPIISKVMETFQPAAVVLQCGADSLTGDRLGCFNLTVKGHGKCVEFVKKYNLPFLMVGGGGYTIRNVSRCWTYETSVALAVEIANELPYNDYFEYFGPDFKLHISPSNMTNQNTSEYLEKIKNRLFENLRMLPHAPGVQIQAIPEDAINDESDDEDKVDKDDRLPQSDKDKRIVPENEYSDSEDEGEGGRRDNRSYKGQRKRPRLDKDTNSNKASSETSSEIKDEKEKGDGADGEESTASNTNSNNNSNNKSDNDAGATANAGSGSGSGSGAGAKGAKENNI

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.